Acta Scientific Nutritional Health (ASNH)(ISSN: 2582-1423)

Review Article Volume 9 Issue 11

The Role of Millet in Gut Modulation and Irritable Bowel Syndrome (IBS) Management: A Review

Maissa Dely* and Melika Mankai

University of Carthage, Research Laboratory: Technological Innovation and Food Security (LR22-AGR01), Higher Institute of Food Industries of Tunisia (ESIAT), Tunis, Tunisia

*Corresponding Author: Maissa Dely, University of Carthage, Research Laboratory: Technological Innovation and Food Security (LR22-AGR01), Higher Institute of Food Industries of Tunisia (ESIAT), Tunis, Tunisia.

Received: September 1266, 2025; Published: October 29, 2025

Abstract

Disorders of gut-brain interaction (DGBI), particularly irritable bowel syndrome (IBS), affect a significant proportion of the global population and are characterized by chronic digestive symptoms without identifiable organic lesions.
Nutrition plays a key role in their management, especially through gluten-free and low-FODMAP diets, which have shown clinical benefits in some patients. However, commonly consumed grains such as wheat and rye are often poorly tolerated in this context.
Millet, an ancient grain that is naturally gluten-free and low in FODMAPs, offers potential as a well-tolerated alternative. It is rich in specific dietary fibers and has positive effects on the gut microbiota, short-chain fatty acid production, and intestinal inflammation.
This review explores the possibility of using millet as a functional ingredient in the creation of products for patients with IBS, aiming for a sustainable, well-accepted, and science-based nutritional approach.

Keywords: Millet; Gut Modulation; Irritable Bowel Syndrome

References

  1. Matias S., et al. “Impact of gluten, alcohol, original extract and batch variation on FODMAP and ATI levels in beer: A comparative study of Spanish macrobreweries’ beers”. Journal of Food Composition and Analysis 147 (2025): 108094.
  2. Verdu EF., et al. “Between Celiac Disease and Irritable Bowel Syndrome: The “No Man’s Land” of Gluten Sensitivity”. The American Journal of Gastroenterology 6 (2009): 1587-1594.
  3. Gibson PR and Shepherd SJ. “Personal view: Food for thought-western lifestyle and susceptibility to Crohn’s disease. The FODMAP hypothesis”. Alimentary Pharmacology and Therapeutics 12 (2005): 1399-1409.
  4. Ispiryan L., et al. “Characterization of the FODMAP-profile in cereal-product ingredients”. The Journal of Cereal Science 92 (2020): 102916.
  5. Eswaran SL., et al. “A randomized controlled trial comparing the low FODMAP diet vs. modified NICE guidelines in US adults with IBS-D”. The American Journal of Gastroenterology 12 (2016): 1824-1832.
  6. Liljebo T., et al. “Presence of fermentable oligo-, di-, monosaccharides, and polyols (FODMAPs) in commonly eaten foods: Extension of a database to indicate dietary FODMAP content and calculation of intake in the general population from food diary data”. BMC Nutrition 1 (2020): 47.
  7. Schmidt M and Raczyk M. “FODMAP reduction strategies for nutritionally valuable baking products: current state and future challenges”. Critical Reviews in Food Science and Nutrition 22 (2024): 8036-8053.
  8. Jacob J., et al. “The nutrition and therapeutic potential of millets: an updated narrative review”. Frontiers in Nutrition 11 (2024): 1346869.
  9. Jayasinghe M., et al. “The Role of Diet in the Management of Irritable Bowel Syndrome: A Comprehensive Review”. Cureus 2 (2024): e54244.
  10. Kumar TS., et al. “Significance of millets for food and nutritional security—an overview”. Discover Food 4 (2024): 73.
  11. Majid A and Priyadarshini CGP. “Millet derived bioactive peptides: a review on their functional properties and health benefits”. Critical Reviews in Food Science and Nutrition 60 (2020): 3342-3351.
  12. Khader V and Maheswari U. “Effect of feeding malted foods on the nutritional status of pregnant women, lactating women and preschool children in Lepakshi Mandal of Ananthapur District, Andhra Pradesh, India”. International Journal of Biotechnology and Molecular Biology Research 4 (2012): 35-46.
  13. Kumar S and Kotwal N. “Millets (Shri Anna) and lifestyle diseases: A healing touch”. Medical Journal Armed Forces India 79 (2023): 249-252.
  14. Gupta RK., et al. “Reduction of phytic acid and enhancement of bioavailable macronutrients in food grains”. Journal of Food Science and Technology 52 (2015): 676-684.
  15. Singh V., et al. “Effects of digested Cheonggukjang on human microbiota assessed by in vitro fecal fermentation”. Journal of Microbiology 59 (2021): 217-227.
  16. Sharma N and Niranjan K. “Foxtail millet: Properties, processing, health benefits, and uses”. Food Reviews International 34 (2018): 329-363.
  17. Sharma S., et al. “Antioxidant activity, total phenolics, flavonoids and antinutritional characteristics of germinated foxtail millet (Setaria italica)”. Cogent Food and Agriculture 1 (2015): 1081728.
  18. Acharya B., et al. “Exploring the antioxidant mechanisms of millet polyphenols: regulation of Nrf2 and NF-κB and their impact on gut microbiota”. Discover Food 4 (2024): 123.

Citation

Citation: Gaissa Dely and Melika Mankai. “The Role of Millet in Gut Modulation and Irritable Bowel Syndrome (IBS) Management: A Review".Acta Scientific Nutritional Health 9.11 (2025): 72-80.

Copyright

Copyright: © 2025 Gaissa Dely and Melika Mankai. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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