Richa Ghai¹1* and Kashish Garg²

¹Associate Professor, Jagannath University, Delhi-NCR, India
²Student Jagannath University, Delhi- NCR, India

*Corresponding Author: icha Ghai, Associate Professor, Jagannath University, Delhi NCR, India.

Received: July 21, 2025; Published: August 15, 2025

Abstract

Iron-deficiency anaemia remains one of the most prevalent nutritional disorders globally, particularly affecting women, chil dren, and adolescents. With growing interest in natural and food-based interventions, Garden Cress Seeds (Lepidium sativum) have emerged as a promising solution due to their high iron content and rich nutritional profile. This review critically examines the nutri tional composition of Garden Cress Seeds, focusing on benefits. The paper synthesizes evidence from existing in-vitro studies, clinical trials, and population-based research, demonstrating the seeds’ effectiveness in improving health. Furthermore, the paper highlights the seeds’ affordability, accessibility, and cultural acceptability, making them suitable for integration into community nutrition strate gies. Overall, this review concludes that Garden Cress Seeds hold significant potential as a natural, sustainable, and effective dietary intervention for the prevention and management of iron-deficiency anaemia.

Keywords: Anaemia; Garden Cress Seeds; Lepidium sativum

References

1. Katyal M., et al. “Development and physico-chemical analysis of value-added chikki using iron rich garden cress seed and exploring its benefits in treatment of anaemic patient”. Food Chemistry Advances 5 (2024): 100763.
2. Mali RG., et al. “Lepidium sativum (Garden cress): A review of contemporary literature and medicinal properties”. Oriental Pharmacy and Experimental Medicine 4 (2007): 331-335.
3. Azene M., et al. “Nutritional, health benefits and toxicity of underutilized Garden Cress Seeds and its functional food products: A review”. Food Production, Processing and Nutrition33 (2022).
4. Vaishnavi Gupta R and Choudhary P. “Botanical description of garden cress (Lepidium sativum L.) plant and physical characteristics of its seeds”. Journal of Pharmacognosy and Phytochemistry 5 (2020): 2424-2428.
5. Kumari R. A descriptive study to assess the “knowledge regarding breast self-examination among adolescent girls” in a selected school of Gaya district, Bihar (Master's dissertation, Indira Gandhi Institute of Medical Sciences, Patna) (2022).
6. John J., et al. “Garden Cress Seeds: A superior grain for the development of nutrient rich cutlets”. International Journal of Chemical Studies4 (2020): 3946-3950.
7. Bhatt TJ., et al. “Hemoglobin, iron deficiency anemia, role of halim seeds to eradicate the ailment - A complete overview”. International Journal for Multidisciplinary Research2 (2023): 1-6.
8. Abu-Khudir R., et al. “Garden cress seed oil abrogates testicular oxidative injury and NF-kB-mediated inflammation in diabetic mice”. International Journal of Molecular Sciences20 (2023): 15478.
9. Bhatia K and Bhasin A. “Exploring the versatile potential of Garden Cress Seeds: Therapeutic applications and industrial utilization: A comprehensive review”. The Pharma Innovation Journal9 (2023): 101-108.
10. Tufail T., et al. “Garden Cress Seeds: A review on nutritional composition, therapeutic potential, and industrial utilization”. Food Science and Nutrition 12 (2024): 3834-3848.
11. Salama AA., et al. “Hypolipidemic and cardioprotective benefits of Garden Cress Seeds in rats compared to atorvastatin”. Journal of Medicinal Plants Studies 6 (2019): 101-108.
12. Abid SF., et al. “Health benefits of Garden Cress Seeds”. Riphah Journal of Allied Health Sciences (2023).
13. Painuli S., et al. “Nutraceutical profiling, bioactive composition, and biological applications of Lepidium sativum L”. Oxidative Medicine and Cellular Longevity (2022): 2910411.
14. Dashora R and Choudhary M. “Development of recipes from Garden Cress Seeds and its effect on anaemic patients”. Food Science Research Journal 2 (2016): 299-305.
15. Hekmatshoar Y., et al. “Evidence for health-promoting properties of Lepidium sativum L.: An updated comprehensive review”. Turkish Journal of Pharmaceutical Sciences6 (2022): 714-723.
16. Yadav S. “A study to assess the effectiveness of structured teaching programme on knowledge regarding polycystic ovarian syndrome among adolescent girls in selected senior secondary school, Faridabad (Master's dissertation, Asian Institute of Nursing Education, Guwahati) (2022).
17. El-Gindy YM., et al. “Reproductive performance and milk yield of rabbits fed diets supplemented with garden cress (Lepidium sativum) seed”. Scientific Reports 12 (2022): 17083.
18. Munda N. “A descriptive study to assess the knowledge regarding ill effects of junk food among adolescents in selected schools of Ranchi, Jharkhand (Master's dissertation, RIMS College of Nursing, Ranchi) (2022).
19. Katyal M., et al. “Development and physico-chemical analysis of value-added Chikki using iron rich garden cress seed and exploring its benefits in treatment of anaemic patient”. Food Chemistry Advances 5 (2024): 100763.
20. Kaur J. “A descriptive study to assess the knowledge regarding prevention of urinary tract infection among adolescent girls in selected school of Jalandhar, Punjab (Master's dissertation, Baba Farid University of Health Sciences, Faridkot) (2022).
21. Singh B., et al. “Lepidium sativum: Its nutritional composition and therapeutic properties”. The Pharma Innovation Journal7 (2022): 15-25.
22. Yadav S. “A study to assess the effectiveness of a planned teaching programme on knowledge regarding cervical cancer and its prevention among adolescent girls in selected school of Bhopal district (Master's dissertation, Barkatullah University, Bhopal) (2022).
23. Khalid L., et al. “Garden cress seed: A review of its functional and medicinal properties”. Journal of Agriculture and Food Research 21 (2025): 101894.
24. Zia-Ul-Haq M., et al. “Compositional study and antioxidant potential of Ipomoea hederacea Jacq. and Lepidium sativum L. seeds”. Molecules9 (2012): 10306-10321.
25. Alsadee SAA. “Hepato-nephroprotective role of Lepidium sativum against oxidative stress induced by dexamethasone in rats”. Indian Journal of Forensic Medicine and Toxicology1 (2021): 2643-2647.
26. Khatun H., et al. “Effects of dietary variations in methionine and lysine levels on the growth performance and carcass characteristics of BLRI-improved hilly chicken”. Egyptian Journal of Veterinary Sciences1 (2025): 1-6.
27. Jagdale YD., et al. “Nutritional profile and potential health benefits of super foods: A review”. Sustainability16 (2021): 9240.
28. Hanan MAAS., et al. “Utilization of Garden Cress Seeds (Lepidium sativum L.) as Natural Source of Protein and Dietary Fiber in Noodles”. International Journal of Pharmaceutical Research and Allied Sciences 3 (2019): 17-28.
29. Vazifeh S., et al. “Anti-inflammatory and immunomodulatory properties of Lepidium sativum”. BioMed Research International (2022): 3645038.
30. vSingh CS., et al. “Exploring potential of fortification by garden cress (Lepidium sativum L.) seeds for development of functional foods-A review”. Indian Journal of Natural Products and Resources3 (2015): 167-175.
31. Mohamed HS., et al. “The modulatory effects of black chia (Salvia hispanica) and garden cress (Lepidium sativum) seeds on Nε-CML formation in streptozotocin-injected rats”. Journal of Herbmed Pharmacology 2 (2023): 250-261.
32. Ibrahim IA., et al. “Ameliorative effect of garden cress (Lepidium sativum L.) seeds ethanolic extract on high fat diet-prompted non-alcoholic fatty liver disease in the rat model: Impact on 3-hydroxy-3-methylglutaryl-coenzyme A reductase and vascular endothelial growth factor”. Advances in Animal and Veterinary SciencesS1 (2020): 1-10.

Citation

Citation: Richa Ghai and Kashish Garg. “Benefits of Lepidium Sativum- A Review".Acta Scientific Nutritional Health 9.9 (2025): 80-91.

Copyright

Copyright: © 2025 Richa Ghai and Kashish Garg. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.