Acta Scientific Nutritional Health (ASNH)(ISSN: 2582-1423)

Comprehensive Review Volume 4 Issue 5

Disturbance in the Substrate Balance Related to Insulin Resistance and Diabetes Mellitus Type 2

Fabiano De Macedo Salgueirosa and Maria Gisele Dos Santos*

Department of Physical Education, Federal University of Paraná, Curitiba, PR, Brazil

*Corresponding Author: Maria Gisele Dos Santos, Department of Physical Education, Federal University of Paraná, Curitiba, PR, Brazil.

Received: March 23, 2020; Published: May 11, 2020

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 Diabetes Mellitus (DM) is considered today as one of the biggest public health problems. It is estimated that in 2030 approximately 366 million people will have some type of DM [1]. Type 2 DM (DM2) is caused mainly by insulin resistance, defined by Hunter and Garvey [2] as “a clinical condition in which a normal or elevated concentration of insulin is observed that produces an attenuated biological response”, manifesting itself 10 - 20 years before the symptoms of DM2 are observed.




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