Acta Scientific Nutritional Health

Short CommunicationVolume 2 Issue 4

Biotherapy and the Immune System in Ageing Science

Ian James Martins1,2,3*

1Centre of Excellence in Alzheimer’s Disease Research and Care, Sarich Neuroscience Research Institute, Edith Cowan University, Nedlands, Australia
2School of Psychiatry and Clinical Neurosciences, The University of Western Australia, Nedlands, Australia
3McCusker Alzheimer’s Research Foundation, Hollywood Medical Centre, Nedlands, Australia

*Corresponding Author: Ian Martins, School of Medical and Health Sciences, Edith Cowan University, Western Australia, Australia.

Received: March 06, 2018; Published: March 27, 2018

Citation: Ian James Martins. “Biotherapy and the Immune System in Ageing Science”. Acta Scientific Nutritional Health 2.4 (2018).


  Nutritional interventions have become important to delay the global diabetes and non-alcoholic fatty liver disease (NAFLD) pandemic. Nutritional biotherapy that activates the heat shock gene Sirtuin 1 (Sirt 1) is essential to prevent immunosenescence that is connected to mitochondrial apoptosis, chronic disease and neurodegeneration. Biotherapy to maintain the immune system require interventions that increase the consumption of Sirt 1 activators, functional foods and bioactive molecules. Low calorie diets are essential to maintain the Sirt 1 regulation of the immune system and autoimmune disease. Plasma Sirt 1 analysis should now be conducted on plasma samples to determine Sirt 1’s role in the defective immune system/autoimmune disease with relevance to diabetes and NAFLD. Sirt 1 analysis with other immunological tests may assist with interpretations relevant to mitochondrial apoptosis and immunological disease. Drugs and immune reactions that regulate immune cell function are now linked to Sirt 1 activation with relevance to hepatic caffeine, xenobiotic and drug metabolism.

Keywords: Biotherapy; Immune System; Chronic Disease; Food Quality; Sirtuin 1; Immunosenescence

Copyright: © 2018 Ian James Martins. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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