Rodríguez-Flores JR¹, Villanueva-Cerda DV², Chávez-Mora IY³, Dávila-Espinoza GS⁴, García-Delgado L¹, Ramírez-Briones E⁴, Martínez-Jiménez MA³ and Mireles-Flores S³*

¹Department of Veterinary Medicine, University Center for Biological and Agricultural Sciences, University of Guadalajara, Mexico
²Veterinary Medicine Undergraduate Student, University Center for Biological and Agricultural Sciences, University of Guadalajara, Mexico
³Animal Production Department, University Center for Biological and Agricultural Sciences, University of Guadalajara, Mexico
⁴Department of Cellular and Molecular Biology, University Center for Biological and Agricultural Sciences, University of Guadalajara, Mexico

*Corresponding Author: Mireles-Flores S, Department of Animal Production, University Center for Biological and Agricultural Sciences, University of Guadalajara, Mexico.

Received: July 26, 2026; Published: August 12, 2026

Abstract

The use of the leaf of Costus pictus D. Don has demonstrated a hypoglycemic effect in the rat model of streptozotocin-induced diabetes. In addition, other species of the same genus and different types of extractions show anti-inflammatory activity. Processing the leaves of this plant to administer experimentally allows a more reasonable approach to study the effects on the physiology of the organism in a comprehensive way and an adequate comparison with the human body. Previously, our group published results on the same treatment with 150-week-old hens of the Lohmann line and in the present work we report: physical-chemical analysis of the plant, its hypoglycemic effect in the rat model and on hens of the Hy Line and 50 weeks of age, as well as on egg production and peripheral blood leukocyte formula. comparing with the aqueous extract of the leaf of Costus pictus D. Don microencapsulated. The same trend was found regarding the hypoglycemic effect in both models and in terms of what was reported in long-lived hens versus young hens, both for production parameters and for the immune response. The relevance of the formulation to be administered in the laying hen model and the strategy to achieve better results in preclinical models with extracts and with respect to application times and probable unwanted effects are discussed.

 Keywords: Costus pictus; Antioxidant; Olive Oil

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Citation

Citation: Mireles-Flores S. et al. “Pilot Test on the Hypoglycemic, Immunomodulatory and Productivity Effect of Costus pictus Liquefied in Wistar Rats and Laying Hens". Acta Scientific Veterinary Sciences 8.2 (2026): 09-20.

Copyright

Copyright: © 2026 Mireles-Flores S. et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.