Acta Scientific Veterinary Sciences (ISSN: 2582-3183)

Review Article Volume 7 Issue 10

The Livestock with Unique Evolutional Adaptation to North-West Himalayan Region

Birbal Singh*, Gorakh Mal, Rinku Sharma, Devi Gopinath, Gauri Jairath, Ajayta Rialch and Suma N

ICAR-Indian Veterinary Research Institute, Regional Station, Palampur, H.P, India

*Corresponding Author:Birbal Singh, ICAR-Indian Veterinary Research Institute, Regional Station, Palampur, H.P, India.

Received: May 08, 2025; Published: September 29, 2025

Abstract

Bioresources are indispensable to the development and sustenance of a national economy. North-West Himalayan Region (NWHR) of Indian subcontinent is bequeathed with a rich, yet unexploited unique resources entailing glaciers, perennial streams and rivulets, climates, plants and animals. Goats, sheep, buffaloes, cattle and camels inhabiting NWHR exhibit distinctive evolutional adaptation to ambient stress. The exclusive adaptive features include physiological i.e., pulmonary and cardiovascular systems, more volume and pulmonary vasculature, and biochemical mechanisms like efficient O2-exchange, and blood O2-exchange at tissue levels. The gut microbiota of these animals enable them to utilize feedstuff enriched with indigestible lignocellulose and anti-nutritional phytochemicals. The genes, genetic pathways regulating adaptation and the metabolic traits should be exploited to improve adaptive performance of high-yielding livestock susceptible to stresses.

Keywords: Evolutional Adaptation; Ambient Stress; Livestock Biodiversity; North-West Himalayas; Genetic Variations; Candidate Genes

References

  1. Singh B., et al. “Steps Toward Sustainable Livestock Development: Technologies to Boost Indigenous Livestock”. In: Advances in Animal Biotechnology. Springer, Cham (2019).
  2. Wu DD., et al. “Special Topic: Convergent Adaptive Evolution Convergent genomic signatures of high-altitude adaptation among domestic mammals”. National Science Review 7 (2020): 952-963.
  3. Singh B., et al. “Rumen Microbiome Transplantation. In: Probiotics as Live Biotherapeutics for Veterinary and Human Health, Volume 1. Springer, Cham (2024).
  4. Mal G., et al. “Milk composition, antioxidant activities and protein profile of Gaddigoat milk”. Journal of Food Biochemistry 42 (2018): e12660.  
  5. Vohra V., et al. “Morphometric and microsatellite-based comparative genetic diversity analysis in Bubalus bubalis from North India”. PeerJ 9 (2021): e11846.  
  6. Singh B., et al. “Isolation of tannase-producing Enterobacter ludwigii GRT-1 from the rumen of migratory goats”. Small Ruminant Research 102 (2012): 172-176.
  7. Sharma D., et al. “Degradation of euptox A by tannase-producing rumen bacteria from migratory goats”. Journal of Applied Microbiology 5 (2017): 1194-1202.
  8. Bhat B., et al. “Identification of potential key genes and pathways associated with the Pashmina fiber initiation using RNA-Seq and integrated bioinformatics analysis”. Scientific Reports 1 (2021): 1766.
  9. Ahlawat S., et al. “Molecular insights into Pashmina fiber production: comparative skin transcriptomic analysis of Changthangi goats and sheep”. Mammalian Genome 2 (2004): 160-169.
  10. Li C., et al. “Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus”. BMC Genomics1 (2022): 140.  
  11. Sharma R., et al. “Genetic diversity estimates point to immediate efforts for conserving the endangered Tibetan sheep of India”. Meta Gene 8 (2019): 14-20.
  12. Sharma SA., et al. “Isolation and characterization of fibrolytic enzymes from sheep rumen bacteria”. International Journal of Probiotics and Prebiotics 12 (2017): 191-198.
  13. Ahmad SF., et al. “Analysis of selection signatures reveals important insights into the adaptability of high-altitude Indian sheep breed Changthangi”. Gene 799 (2021): 145809.
  14. Gera R., et al. “Exploring transcriptomic mechanisms underlying pulmonary adaptation to diverse environments in Indian rams”. Molecular Biology Reports 1 (2024): 1111.
  15. Vasu M., et al. “Genetic insights into fiber quality, coat color and adaptation in Changthangi and Muzzafarnagri sheep: A comparative skin transcriptome analysis”. Gene 891 (2024): 147826.
  16. Arora R., et al. “Skeletal muscle transcriptomics of sheep acclimated to cold desert and tropical regions identifies genes and pathways accentuating their diversity”. International Journal of Biometeorology 9 (2024): 1811-1821.
  17. Guang-Xin E., et al. “Whole-genome analysis identifying candidate genes of altitude adaptive ecological thresholds in yak populations”. Journal of Animal Breeding and Genetics 136 (2019): 371-377.
  18. Guang-Xin E., et al. “Genome-wide selective sweep analysis of the high-altitude adaptability of yaks by using the copy number variant”. 3 Biotech6 (2020): 259.
  19. West JB. “Physiological Effects of Chronic Hypoxia”. The New England Journal of Medicine 20 (2017): 1965-1971.
  20. Xue Y., et al. “Anaerobic Fungi Isolated From Bactrian Camel Rumen Contents Have Strong Lignocellulosic Bioconversion Potential”. Frontiers in Microbiology 13 (2022): 888964.
  21. Naing YP., et al. “Rumen fermentation shifts and microbial dynamics in mid-lactating Holstein dairy cows experiencing heat stress and subsequent recovery periods”. Animal Bioscience 4 (2025): 641-654.  
  22. Tiwari M., et al. “Selection of species specific panel of reference genes in peripheral blood mononuclear cells of native livestock species adapted to trans-Himalayan region of Leh-Ladakh”. Scientific Reports 1 (2022): 18473.  
  23. Sharma V., et al. “Antioxidative activity and protein profile of skim milk of Gaddi goats and hill cattle of North West Himalayan region”. Veterinary World 10 (2019): 1535-1539.
  24. Dar AH., et al. “Genetic characterization and population structure of different coat colour variants of Badri cattle”. Molecular Biology Reports 11 (2020): 8485-8497.
  25. Rahman JU., et al. “Genetic diversity, population structure analysis and codon substitutions of Indicine Badri cattle using ddRAD sequencing”. 3 Biotech 2 (2024): 46.
  26. Singh B., et al. “The domesticated buffalo - An emerging model for experimental and therapeutic use of extraembryonic tissues”. Theriogenology 151 (2020): 95-102.
  27. Singh B., et al. “Reproductive biotechniques in buffaloes (Bubalus bubalis): status, prospects and challenges”. Reproduction, Fertility and Development 4 (2009): 499-510.
  28. Devi G., et al. “Migratory Gaddi sheep and goats as potential carriers of Theileria infection: a molecular survey”. Tropical Animal Health and Production 2 (2021): 302.
  29. Kumar A., et al. “Transcriptomic diversity in longissimus thoracis muscles of Barbari and Changthangi goat breeds of India”. Genomics4 (2021): 1639-1646.
  30. Dinesh K., et al. “Evaluation of morphological traits using multivariate techniques in Kotdhar goat native to Shivalik hill region of Himachal Pradesh”. Tropical Animal Health and Production 2 (2024): 64.
  31. Ahmad HI., et al. “Genomic insights into Yak (Bos grunniens) adaptations for nutrient assimilation in high-altitudes”. Scientific Reports 1 (2024): 5650.
  32. Li G., et al. “Whole-genome resequencing reveals genetic diversity, differentiation, and selection signatures of yak breeds/populations in Qinghai, China”. Frontiers in Genetics 13 (20203): 1034094.
  33. Ahlawat S., et al. “Advancing equine genomics: the development of a high density Axiom_Ashwa SNP chip for Indian horses and ponies”. Functional and Integrative Genomics 6 (2024): 195.
  34. Verma P., et al. “Identification of Internal Reference Genes in Peripheral Blood Mononuclear Cells of Cattle Populations Adapted to Hot Arid Normoxia and Cold Arid Hypoxia Environments”. Frontiers in Genetics 12 (2022): 730599.
  35. Tiwari M., et al. “Selection signatures for high altitude adaptation in livestock: A review”. Gene 927 (2024): 148757.

Citation

Citation: Birbal Singh., et al. “The Livestock with Unique Evolutional Adaptation to North-West Himalayan Region".Acta Scientific Veterinary Sciences 7.10 (2025): 57-67.

Copyright

Copyright: © 2025 Birbal Singh., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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