Lawan Adamu*

Department of Veterinary Medicine, University of Maiduguri, Faculty of Veterinary Medicine, Nigeria

*Corresponding Author: Anjali Kumari, Research Scholar, Department of Bioengineering and Biotechnology, Birla Institute of Technology Mesra Ranchi Jharkhand, India.

Received: Jume 17, 2025; Published: September 10, 2025

Abstract

Equine laminitis, an agonizing hoof disease with unknown origins, has long tormented horses' hooves. A recent work in epitranscriptomics, which investigates RNA alterations that affect gene expression after transcription, sheds fresh light on the molecular mechanisms underlying this disease. This in-depth study looks into the relationship between RNA changes, metabolic problems, and inflammatory pathways in laminitis. Examining key epitranscriptomic regulators such as N6-methyladenosine (m6A), pseudouridine, and inosine indicates their potential role in disease genesis and treatment strategies. The incorporation of contemporary sequencing technology and individualized epitranscriptomic therapy has the potential to improve the accuracy of laminitis diagnosis and treatment, ushering in a new era in horse health care.

Keywords: RNA Epigenetics; Laminar Inflammation; N6-Methyladenosine; Pseudouridine; Inosine

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Citation

Citation: Lawan Adamu. “The Epitranscriptomic Edge: Revolutionizing Equine Laminitis through RNA Modifications".Acta Scientific Veterinary Sciences 7.10 (2025): 03-10.

Copyright

Copyright: © 2025 Lawan Adamu. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.