Acta Scientific Veterinary Sciences (ISSN: 2582-3183)

Research Article Volume 7 Issue 9

Evaluation of Heart Diseases in Rabbits with Echocardiography Cardiac Diseases

Melahat TOKER*

Department of Physiology, Faculty of Health Sciences, Yuksek Ihtisas University, Ankara, Turkey

*Corresponding Author: Melahat TOKER, Department of Physiology, Faculty of Health Sciences, Yuksek Ihtisas University, Ankara, Turkey.

Received: August 19, 2025; Published: August 27, 2025

Abstract

The New Zealand White rabbit laboratory animal has an important place in cardiological studies as well as in many scientific studies. In this respect, echocardiographic methods are the gold standard in the diagnosis of cardiac diseases in veterinary medicine. Cardiac diseases such as congestive heart failure, congenital heart disease, cardiomyopathy, tricuspid, mitral valve disease and diastolic dysfunction are observed in rabbits. Therefore, periodic echocardiographic studies are required in healthy rabbits. All rabbits were examined by color Doppler echocardiographic method using a 5-7.5 mHz transducer. In the studies, images were obtained from the 2nd to 4th intercostal space, parasternal long axis, parasternal short axis, apical four-chamber and modified four-chamber windows using two-dimensional (2D) mode, M-mode and color Doppler echocardiography methods. In the examination, the anatomy and functions of the rabbit heart were examined one by one. When the values obtained in this study were compared with the studies conducted on cats and dogs in routine veterinary medicine, it was observed that rabbits also had cardiac problems. In addition, it was determined that the changes in right ventricular parameters were compatible with the changes in left ventricular occupancy parameters. Our aim in this study is to bring rabbits into our lives not only as laboratory animals but also as healthy pets.

Keywords: Diagnostic Techniques; Echocardiography; Heart, Rabbit

References

  1. Liu R., et al. “Transfection of human hepatocyte growth factor gene inhibits advancing pulmonary arterial hypertension induced by shunt flow in a rabbit model”. Transplantation Proceedings 2 (2013): 705-712.
  2. Ashida T., et al. “Basal cardiomyopathy develops in rabbits with ventricular tachyarrhythmias induced by a single injection of adrenaline”. International Heart Journal1 (2014): 78-83.
  3. Lord B., et al. “Congestive heart failure in two pet rabbits”. Journal of Small Animal Pracite 52 (2011): 46-50.
  4. İriadam M and Toker M. “Ekokardiyografi ve Veteriner Hekimlikte kullanımı” (2024).
  5. Casamian-Sorrosal D., et al. “M-mode, two dimensional and Doppler echocardiographic findings in 40 healthy domestic pet rabbits”. Journal of Veterinary Cardiology2 (2014): 101-108.
  6. Gan LM., et al. “Amplitude and velocity of mitral annulus motion in rabbits”. A Journal of Cardiovascular Ultrasound and Allied Techologies 4 (2004): 313-317.
  7. Toker M and Sağmanligil V. “Tavşanlarda Doppler yöntemi ile ekokardiyografik yöntemin değerlendirilmesi (2002).
  8. Dornas WC., et al. “Experimental atherosclerosis in rabbits”. Arquivos Brasileiros de Cardiologia 2 (2010): 272-280.
  9. Gava FN., et al. “Doxorubicin induced dilated cardiomyopathy in a rabbit model: An update. Research in Veterinary Science 1 (2013): 115-121.
  10. Vichit P., et al. “Changes of cardiac function in diabetic dogs”. Journal of Veterinary Cardiology 6 (2018): 438-450.
  11. Redrobe S. “Ultrasonography. In: Harcourt-Brown F, Chitty J (2013). BSAVA Manual of Rabbit Surgery, Dentistry and Imaging. Cheltenham: BSAVA press (2013).
  12. Takahashi K and Tanaka R. “Key factors of diastolic dysfunction and abnormal left ventricular relaxation in diabetic rats”. Journal of Medical Ultrasonics 3 (2020): 347-356.
  13. Kipipatkun P., et al. “The Utility of Intraventricular Pressure Gradient for Early Detection of Chemotherapy-Induced Subclinical Cardiac Dysfunction in Dogs”. Animals (basel) 4 (2021): 1122.
  14. Harcourt-Brown F. “Textbook of Rabbit Medicine”. Oxford: Reed Educational and Professional Publishing Ltd (2002).
  15. Zamora M and Villena JV. “Contribution of impaired insulin signaling to the pathogenesis of diabetic cardiomyopathy”. International Journal of Molecular Sciences11 (2019): 2833.
  16. Nagueh SF., et al. “Tissue Doppler imaging consistently detects myocardial contraction and relaxation abnormalities, irrespective of cardiac hypertrophy, in a transgenic rabbit model of human hypertrophic cardiomyopathy”. Circulation 12 (2000): 1346-1350.
  17. Pelosi A., et al. “Cardiac tissue Doppler and tissue velocity imaging in anesthetized New Zealand white rabbits”. Journal of the American Association for Laboratory Animal Science 3 (2011): 317-321.
  18. Boon J. “The Two Dimensional Echocardiographic Exam. In: Boon J”. Veterinary Echocardiography. Chichester, UK: Jon Willey and Sons (2011).
  19. Sunilchandra U., et al. “Analgesics in animal pain management”. The Pharma Innovation Journal 5 (2000): 205-209.

Citation

Citation: Melahat TOKER. “Evaluation of Heart Diseases in Rabbits with Echocardiography Cardiac Diseases".Acta Scientific Veterinary Sciences 7.9 (2025): 30-37.

Copyright

Copyright: © 2025 Melahat TOKER. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate35%
Acceptance to publication20-30 days
Impact Factor1.008

Indexed In





News and Events


Contact US