Shavi Ritika and NL Selokar and MK Singh*

Embryo Biotechnology Lab, Animal Biotechnology Division, ICAR- National Dairy Research Institute, Haryana, India

*Corresponding Author: MK Singh, Embryo Biotechnology Lab, Animal Biotechnology Division, ICAR- National Dairy Research Institute, Haryana, India.

Received: June 13, 2025; Published: July 23, 2025

Abstract

This article reviews the crucial roles of microRNAs (miRNAs) in embryo development and quality. It explains how miRNAs man age key developmental stages by regulating gene expression, epigenetic changes, and the way cells respond to oxidative stress. The review notes that proper miRNA function is vital for processes such as cell cycle progression, maintaining pluripotency, and tissue differentiation. When miRNAs do not function correctly, it can lead to developmental issues, improper epigenetic regulation, abnor mal trophoblast development, and poor vascularization, all of which can ultimately affect embryo quality. Unique miRNA profiles have been found in high-quality embryos, indicating their potential as non-invasive markers for evaluating embryo competence in assisted reproductive technologies (ART). Highlighting the critical significance of miRNAs as well as the restrictions and difficulties in clinical applications of miRNAs related to reproductive biology, the article additionally addresses potential future uses of miRNAs and extracellular vesicles to improve embryo selection and outcomes in ART.

Keywords: miRNA; Embryos; Pluripotency; Epigenetic Modifications

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Citation

Citation: MK Singh., et al. “MicroRNA: The Hidden Influencer of Embryo Quality". Acta Scientific Veterinary Sciences 7.8 (2025): 19-26.

Copyright

Copyright: © 2025 MK Singh., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.