Saurabh S Suryawanshi¹ , Pranav H Pawar ¹ , Sanket S Salunkhe¹ , Suraj S Kalyankar¹ , Pranali R Gore¹ , Pooja S Khade ¹ , Vedant S Nalawade ¹ , Aishwarya D Koshti ¹ and Firoj A Tamboli ² *

¹ UG Students, Bharati Vidyapeeth College of Pharmacy, Near Chitranagari Kolhapur, Maharashtra, India
² Department of Pharmacognosy, Bharati Vidyapeeth College of Pharmacy, Near Chitranagari, Kolhapur, Maharashtra, India

*Corresponding Author: Firoj A Tamboli, Department of Pharmacognosy, Bharati Vidyapeeth College of Pharmacy, Near Chitranagari, Kolhapur, Maharashtra, India.

Received: February 09, 2026 Published: February 28, 2026

Abstract

Lignans are a distinctive class of phytoestrogenic polyphenol which occur extensively in the plant kingdom particularly in seeds, grains, vegetables and fruits. Over the last few years, scientists have developed increased interest in lignan since they possess diverse biological effects. Lignans would make good antioxidants and anti-inflammatories, heart protectors and may be useful in combating cancer. Transformation of the lignans found in plants to enterodiol and enterolactone which are mammalian enterolignans occurs by the activity of gut bacteria. This establishes a significant connection between food, intestinal health, and health. This paper gives a closer examination of the dietary lignans including their natural sources, molecular structure, metabolic pathways, rate of absorption and their role in the biological system. It emphasizes their role in preventing chronic illnesses, hormonal balance as well as in the interaction between the gut and the brain. According to scientific evidence, foods that are rich in lignans, including flax seed, sesame, rye, and whole grains are the indispensable elements of a diet that enhance the metabolic attributes and cardiovascular well-being. The review also covers recent innovations in extraction, the process methods and production of functional food stuffs.

Keywords: Lignans; Phytoestrogens; Gut Microbiota; Functional Foods; Antioxidant; Cardiovascular Health

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Citation

Citation: Firoj A Tamboli., et al. “Lignan-Based Phytoestrogenic Nutraceuticals and Their Role in Human Health". Acta Scientific Pharmaceutical Sciences 10.3 (2026): 23-29.

Copyright

Copyright: © 2026 Firoj A Tamboli., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.