Phytochemical Evaluation and Pharmacological Screening of Saraca celebica W.J Wilde
and Asparagus fallax Plant Extract for Central and Peripheral Analgesic Activity
Asha Jyothi V*, Siddiqua Nida and Syeda Safoora Imad
Department of Pharmacology, Shadan Women’s College of Pharmacy, Khairtabad, Hyderabad, India
*Corresponding Author: Asha Jyothi V, Department of Pharmacology, Shadan Women’s College of Pharmacy, Khairtabad, Hyderabad, India.
Received:
March 24, 2025; Published: April 09, 2025
Nutraceuticals such as Saraca celebica W.J Wilde and Asparagus fallax were extracted by ethanolic extract. These extracts were subjected to examine pharmacological action by centrally acting analgesic activity using tail immersion method and peripheral acting analgesic activity using acetic acid induced writhing test in rats. The crude extract of the plant was found to have significant (p < 0.01) analgesic activity at the oral dose in the test models of tail immersion, Saraca celebica W.J Wilde showed increased time latency than Asparagus fallax, where as in acetic acid induced writhing test Asparagus fallax showed reduced number of writhes than Saraca celebica W.J Wilde at dose levels which have significant (p < 0.001) compared to control. The result obtained support the use of the plants Saraca celebica W.J Wilde and Asparagus fallax in painful condition acting both centrally and peripherally.
Keywords: Saraca celebica W.J Wilde Analgesic Activity; Asparagus fallax
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