Amana Parveen, Shashi Kiran Misra, Anupriya Kapoor, Yuthika Narayan, Shivam Kumar Verma, Pramod Chauhan and Ajay Kumar*
School of Pharmaceutical Sciences, CSJM University, Kanpur, India
*Corresponding Author: Ajay Kumar, School of Pharmaceutical Sciences, CSJM University, Kanpur, India.
Received: October 05, 2021; Published: October 25, 2021
Nitrogen-containing heterocyclic combinations are widely explored in the synthesis and development of a variety of chemicals in therapeutic sciences. Pyrazolines are one of the major heterocyclic molecules that take a crucial part by the virtue of their pharmacological properties, pyrazolines are remarkable and enormousnitrogen-containing 5-membered heterocyclic combinations and various methods for their mixing have been shown. Several subordinates of pyrazoline were found to have significant normal activities, which revived the development of assessment in this area. They have a couple of prominent effects, similar to antimicrobial, antimycobacterial, antifungal, antiamoebic, alleviating, torment easing, upper and anticancer activities. 2-pyrazolines give off an impression of being the regularly pondered pyrazoline-type compounds. These combinations are by and large prepared from the cyclization of chalcones with hydrazine and its auxiliaries under alcoholic conditions. Pyrazolines are the diminished types of pyrazoles Subsequently, a tremendous number of such pyrazolines using particularly designed methods for their arranging have been portrayed in this article. The current study gives an understanding viewpoint to pyrazolines synthesis and its biological activities.
Keywords: Pyrazole; Pyrazoline; Synthesis; Biological Activities; Pharmacological Properties; Chalcone
Citation: Ajay Kumar., et al. “Synthetic Approaches and Biological Activities of Heterocyclic Pyrazoline". Acta Scientific Pharmaceutical Sciences 5.11 (2020): 59-69.
Copyright: © 2020 Ajay Kumar., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.