Acta Scientific Pharmaceutical Sciences (ASPS)(ISSN: 2581-5423)

Research Article Volume 5 Issue 10

Essential Oil Composition and Antimicrobial Activities of Lavandula pubescens, Marrubium vulgare and Meriandra bengalensis from Yemen

Yani AA1, Eldahshan OA2,3*, Hassan SA4, Elwan ZA4 and Ibrahim HM1

1Biology Department, Botany Section, Faculty of Science, Sanaa University, Yemen
2Pharmacognosy Department, Faculty of Pharmacy, Ain Shams University, Egypt
3Center for Drug Discovery Research and Development, Ain Shams University, Egypt
4Botany Department, Faculty of Science, Ain Shams University Cairo, Egypt

*Corresponding Author: Eldahshan OA, Faculty of Pharmacy, Department of Pharmacognosy, Ain Shams University, Cairo, Egypt.

Received: August 02, 2021; Published: September 18, 2021

Abstract

  In Yemen, family Lamiaceae is one of the most important families due to its use in folk medicine and for the commercial production of essential oils. In this study, three Lamiaceae plants; Lavandula pubescens Decne, Marrubium vulgare L. and Meriandra bengalensis (Roxb.) Benth, were chemically investigated by GC/MS as well as their antimicrobial activity was assessed using agar-well diffusion method. The major compounds in Lavandula pubescens oil were carvacrol (54.98%), thymol methyl ether (12.15%) and Z-caryophyllene (4.47%), while those of Marrubium vulgare were Z-caryophyllene (10.95%), octadecanol (10.44%) and α-bisabolene (9.72%). Meriandra bengalensis contained camphor (64.87%) as a major compound with 1,8 cineole (12.16%) and camphene (11.96%). The strongest antimicrobial activity was observed in Lavandula pubescens against Klebsielle pneumoniae (1.95 μL/mL) which is higher than that of gentamycin, Enterobacter cloacae (0.98 μL/mL), and Bacillis subtilis (0.49 μL/mL) that are similar in activity to that of standards (gentamycin and ampicillin). Oils of Marrubium vulgare L. and Meriandra bengalensis exhibited a range of activities between weak and none. Our result concludes that Lavandula pubescens possess pronounced antimicrobial activity against Klebsielle pneumoniae, Enterobacter cloacae and Bacillis subtilis giving it a highly medicinal impact value to be further studied in vivo against different types of microbial infectious diseases

Keywords: Lamiaceae; Volatile Oil; Antimicrobial Activity

References

  1. Cantino PD., et al. “A comparison of phylogenetic nomenclature with the current system: a botanical case study”. System Biology 46 (1997): 313-331.
  2. Kadereit J and Kubitzki K. “The Families and Genera of Vascular Plants VII. Flowering Plants Dicotyledons: Lamiales (Except Acanthaceae Including Avicenniaceae), Flowering Plants ⋅ Dicotyledons”. Springer Berlin Heidelberg, Berlin, Heidelberg (2004).
  3. Al-Khyat SH., et al. “Antimicrobial activity of Lavandula pubescens essential oil from two places In Yemen”. Journal of Advances in Biology 4 (2014): 446-454.
  4. Chorianopoulos NG., et al. “Seasonal variation in the chemical composition of the essential oils of Satureja species and their MIC assays against foodborne pathogens”. Food Chemistry 54 (2006a): 3139-3145.
  5. Gayathiri K., et al. “Potential pharmacological uses of natural products from Lamiaceae”. International Journal of Pharmaceutical Sciences Review and Research 5 (2016): 21-34.
  6. Chorianopoulos NG., et al. “Essential oils of Lamiaceae family taxa as natural preservatives of food preparations”. Food Chemistry2 (2007): 202-215.
  7. Nezhadali A., et al. “Chemical variation of leaf essential oil at different stages of plant growth and in vitro antibacterial activity of Thymus vulgaris Lamiaceae from Iran”. Journal of Basic and Applied Sciences 3 (2014): 87-92.
  8. Tassew H., et al. “Microbial flora and food borne pathogens on minced meat and their susceptibility to antimicrobial agents”. Ethiopian Journal of Health Sciences 20 (2010): 137-143.
  9. Vasickova P., et al. “Viruses as a cause of foodborne diseases: a review of the literature”. Veterinary Medicine Czech 50 (2005): 89-104.
  10. Pierce SE., et al. “Detection and identification of Salmonella enterica, Escherichia coli, and Shigella spp. via PCR-electrospray ionization mass spectrometry: isolate testing and analysis of food samples”. Applied and Environmental Microbiology 78 (2012): 8403-8411.
  11. Burt S. “Essential oils: their antibacterial properties and potential applications in foods--a review”. International Journal of Food Microbiology 94 (2004): 223-253.
  12. Azab SS., et al. “Anti-inflammatory and gastroprotective potential of leaf essential oil of Cinnamomum glanduliferum in ethanol-induced rat experimental gastritis”. Pharmaceutical Biology 55 (2017): 1654-1661.
  13. Eldahshan OA and Halim FA. “Comparison of the composition and antimicrobial activities of the essential oils of green branches and leaves of Egyptian Navel orange (Citrus sinensis (L.) osbeck var. malesy)”. Chemistry and Biodiversity 13 (2016): 1-5.
  14. Taha AS and Eldahshan OA. “Chemical characteristics, antimicrobial and cytotoxic activities of the essential oil of Egyptian Cinnamomum glanduliferum Bark”. Chemistry and Biodiversity 11 (2017): e1600443e1600443.
  15. Adams RP. “Identification of essential oil components by gas chromatography/mass spectrometry”. Allured Publishing Corporation, Illinois, USA, 4th Edition (2007).
  16. Bauer AW., et al. “Antibiotic susceptibility testing by a standardized single disk method”. American Journal of Clinical Pathology 45 (1996): 493-496.
  17. Farraro MJ., et al. “Performance Standards for Antimicrobial Disk Susceptibility Tests Approved Standard M2-A7”. 7th Edn, National Committee for Clinical Laboratory Standards: Wayne, PA, USA (2000): 1-26.
  18. Ghavam M., et al. “Extraction of essential oil from Dracocephalum kotschyi Boiss. (Lamiaceae), identification of two active compounds and evaluation of the antimicrobial properties”. Journal of Ethnopharmacology 267 (2021): 113513.
  19. Ghavam M., et al. “Chemical composition and antimicrobial activity of essential oils obtained from leaves and flowers of Salvia hydrangea DC. ex Benth”. Scientific Report 10 (2020): 15647.
  20. Al-Badani RN., et al. “Variations in essential oil compositions of Lavandula pubescens (Lamiaceae) aerial parts growing wild in Yemen”. Chemistry and Biodiversity3 (2017): 3.
  21. Bayir B., et al. “Chemical composition of essential oil from Marrubium vulgare L. Leaves”. 6 (2014): 44-50.
  22. Bokaeian M., et al. “Phytochemical analysis antibacterial activity of Marrubium vulgare L against Staphylococcus aureus in vitro”. Zahedan Journal of Research in Medical Sciences 16 (2014): 60-64.
  23. Said-Al Ahl HA., et al. “Essential oil composition of Marrubium vulgare L. cultivated in Egypt”. International Journal of Plant Science and Ecology 1 (2015): 138-141.
  24. Ultee A., et al. “The phenolic hydroxyl group of carvacrol is essential for action against the food-borne pathogen Bacillus cereus”. Applied and Environmental Microbiology (2002): 1561-1568.
  25. Xu J., et al. “The antibacterial mechanism of carvacrol and thymol against Escherichia coli”. Letter of Applied of Microbiology 3 (2008): 174-179.
  26. Rana VS and Basques MA. “Constituents of the essential oil of Meriandra bengalensis Benth. leaves from India”. Journal of Essential Oil Research 21 (2009): 22-23.
  27. Golparvar R., et al. “Essential oil composition of Marrubium vulgare L. from Iran”. Journal of Herbal Drugs 6 (2015): 1-5.
  28. Sartoratto A., et al. “Composition and antimicrobial activity of essential oils from aromatic plants used in Brazil”. Brazilian Journal of Microbiology 35 (2004): 275-280.
  29. Duarte MC., et al. “Activity of essential oils from Brazilian medicinal plants on Escherichia coli”. Journal of Ethnopharmacology 4 (2007): 197-201.
  30. Kachur K and Suntres Z. “The antibacterial properties of phenolic isomers, carvacrol and thymol”. Critical Reviews in Food Science and Nutrition 16 (2019): 1-12.
  31. Chimnoi N., et al. “Characterization of essential oil from Ocimum gratissimum leaves: Antibacterial and mode of action against selected gastroenteritis pathogens”. Microbe Pathogen 118 (2018): 290-300.
  32. Kotan R., et al. “Antibacterial activities of essential oils and extracts of Turkish Achillea, Satureja and Thymus species against plant pathogenic bacteria”. Journal of the Science of Food and Agriculture 15 (2010): 145-160.
  33. Almeida KCR., et al. “Biological properties and chemical composition of essential oil from Nectandra megapotamica (Spreng.) Mez. leaves (Lauraceae)”. Natural Product Research 14 (2019): 1-5.
  34. Dahham SS., et al. “The anticancer, antioxidant and antimicrobial properties of the Sesquiterpene β-Caryophyllene from the Essential Oil of Aquilaria crassna”. Molecules7 (2015): 11808-11829.

Citation

Citation: Eldahshan OA., et al. “Essential Oil Composition and Antimicrobial Activities of Lavandula pubescens, Marrubium vulgare and Meriandra bengalensis from Yemen". Acta Scientific Pharmaceutical Sciences 5.10 (2021): 50-58.

Copyright

Copyright: © 2021 Eldahshan OA., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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