Gurkan Atay* and Seher Erdoğan

Department of Pediatric Critical Care, Health Science University, Umraniye Research and Training Hospital, Istanbul,Turkey

*Corresponding Author: Gurkan Atay, Department of Pediatric Critical Care, Health Science University, Umraniye Research and Training Hospital, Istanbul,Turkey.

Received: May 03, 2021; Published: January 13, 2022

Abstract

Objective: Hypoalbuminemia is a frequent condition among patients admitted to pediatric intensive care unit (PICU). The aim of the present study was to determine the prevalence of hypoalbuminemia among critically ill pediatric patients, and to assess its relationship with prognosis.

Materials and Methods: Age, sex, admission diagnosis, Pediatric Risk of Mortality (PRISM) scores, serum total protein and albumin levels, mechanical ventilation (mv) need, number of days on mv, number of PICU days, number of hospital days, and prognosis were recorded among patients admitted to PICU between May 2017 and May 2018. The patients were grouped into two groups on the basis of their serum albumin level; those with hypoalbuminemia were assigned to Group 1 and those without to Group 2.

Results: The study enrolled a total of 126 pediatric patients of whom 64 (50.8%) were female and 62 (49.2%) were male. The mean age of the study population was 64.66 ± 71.28 months. One hundred and five (83.3%) patients survived and 21 (16.7%) died. Forty-six (36.5%) patients had hypoalbuminemia. In patients assigned to Group 1 the need for mechanical ventilation was significantly greater (p:0.007), but there was no significant difference between the number of mv days (p:0.64). Group 1 had a significantly greater PRISM score, a significantly longer hospital stay, and a significantly greater mortality rate (p:0.000, p:0.013, and p:0.000, respectively). No significant difference was seen for the number of PICU days. A prognosis analysis revealed that the survivor group had a higher mean age, less mv need, shorter hospitalization and mv time, and lower serum total protein and albumin levels.

Conclusion: We suggest that serum albumin level is an important prognostic marker as it is a simple, specific, and low-cost parameter that is routinely used in most PICUs.

Keywords: Inflammatory Bowel Disease; Crohn’s Disease; Ulcerative Colitis; Faecal Calprotectin; Endoscopy; Diagnosis; Biomarker

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Citation

Citation: Gurkan Atay and Seher Erdoğan. “Serum Albumin Level in Critically Ill Pediatric Patients". Acta Scientific Paediatrics 5.2 (2022): 03-07.

Copyright

Copyright: © 2022 Gurkan Atay and Seher Erdoğan. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.