Acta Scientific Paediatrics (ISSN: 2581-883X)

Case Report Volume 3 Issue 12

Fixed Drug Eruption Induced by Paracetamol - A Case Report

Liliana Sá1*, Cátia Leitão2, Jorge Romariz3, Herculano Costa3, Fátima Praça3 and Cláudia Pedrosa3

1Pediatrics and Neonatology Department, Centro Hospitalar de Entre-o-Douro e Vouga, Portugal
2Pediatrics Department, Centro Hospitalar de Vila Nova de Gaia/Espinho, Portugal
3Pediatrics Department, Pediatric Immunoallergology and Pulmonology Unit, Centro Hospitalar de Vila Nova de Gaia/Espinho, Portugal

*Corresponding Author: Liliana Sá, Department of Pediatrics and Neonatology, Centro Hospitalar de Entre Douro e Vouga, Portugal.

Received: October 28, 2020; Published: November 30, 2020

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Abstract

Fixed drug eruption can manifest as one or multiple lesions and may be caused by various types of drugs. Paracetamol is one of the common drugs prescribed as analgesic–antipyretic agent in all age group of patients. Its severity spectrum is highly heterogeneous. Fixed drug eruption is a well-reported, but uncommon side-effect of paracetamol, usually the classic, pigmenting type most commonly found in children and adolescents. The authors report the case of an adolescent with this rare entity, warning of its clinical suspicion in cases of recurrent skin drug reactions always in the same location.

Keywords: Drug Eruption; Paracetamol; Antipyretic; Fixed Drug Eruption; Adverse Drug Reaction

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References

  1. Brocq L. “Eruption erythemato-pigmentee fixe due a l'antipyrine”. Annales de Dermatologie et de Vénéréologie. 5 (1894): 308-313.
  2. Bentur Y., et al. “Dipyrone overdose”. Journal of Toxicology: Clinical Toxicology. 42.3 (2004): 261-265.
  3. Tetsuo S., et al. “Fixed drug eruption”. UpToDate (2019).
  4. Hire RC., et al. “Paracetamol induced fixed drug eruption: A case report”. International Journal of Basic and Clinical Pharmacology 3 (2014): 399-400.
  5. Weedon D. “The lichenoid reaction pattern (‘interface dermatitis’)”. Weedon's Skin Pathology. 2nd London: Churchill Livingstone (2002): 42-43.
  6. Dhar S., et al. “Fixed drug eruption due to ciprofloxacin”. British Journal of Dermatology. 134 (1996): 156-158.
  7. Svensson CK., et al. “Cutaneous drug reactions”. Pharmacological Reviews 53 (2000): 357-379.
  8. Breathnach S. M. “Drug reactions”. Rook’s Textbook of Dermatology. 8th Hobokan, New Jersey: Wiley-Blackwell 4 (2010).
  9. Mahboob A., et al. “Drugs causing fixed eruptions: a study of 450 cases”. International Journal of Dermatology 37 (1998): 833.
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Citation

Citation: Liliana Sá., et al. “Fixed Drug Eruption Induced by Paracetamol - A Case Report”. Acta Scientific Paediatrics 3.12 (2020): 27-29.




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Acceptance rate33%
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Impact Factor1.197

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