Acta Scientific Paediatrics (ISSN: 2581-883X)

Review Article Volume 3 Issue 10

Incidence of Corona Virus Disease 2019 (COVID-19) of Neonates at a Tertiary Care Hospital in Bangladesh

Maksudur Rahman1*, Kinkar Ghosh2, Md Mahbubul Hoque3 and M Monir Hossain3

1Associate Professor, Neonatology, Bangladesh Institute of Child Health (BICH), Dhaka Shishu (Children) Hospital, Bangladesh
2Epidemiologist, Dhaka Shishu (Children) Hospital, Bangladesh
3Professor, Neonatology, Bangladesh Institute of Child Health (BICH), Dhaka Shishu (Children) Hospital, Bangladesh

*Corresponding Author: Maksudur Rahman, Associate Professor, Neonatology, Bangladesh Institute of Child Health (BICH), Dhaka Shishu (Children) Hospital, Bangladesh.

Received: July 09, 2020; Published: September 11, 2020



Background: Corona virus disease 2019 (COVID-19) has become global pandemic. It affects mainly adult with serious devastating effect in some cases. It is less in children, even more less in neonates. But to date with increasing surveillances number of neonates with COVID -19 are increasing.

Methods: This cross sectional study was conducted from April 2000 to June 2000 at Dhaka Shishu (Children) Hospital in Bangladesh. All admitted neonates with COVID-19 were taken as cases. Neonate with suspected COVID-19 were tested for SARS-CoV2 virus by Rt PCR. Criteria for test were H/o maternal test positive, relatives test positive, resident of risk area and neonates with abnormal clinical courses such as respiratory distress, not responded to conventional treatment and abnormal chest x-ray. Data regarding gestational age, birth weight, gender, positive cases and others findings were collected and analyzed. Statistics analysis was done by SPSS version 17.

Results: During this study period total 1007 neonates were admitted. Among them 20 (2%) cases were COVID-19. Among the cases with covid19 male were 13 (65%) and female 7 (35%). Male and female ratio was 1.9:1. Term baby was 17 (85%) and preterm 3 (15%). Mean weight were 2618 ± 235 gms. Eight (40%) cases with COVID 19 lived in Dhaka and 12 (60%) cases in outside of Dhaka. Only 2 (10%) cases were positive for SARS- CoV2 virus by Rt PCR within 3 days but after 24 hours of age of neonates. Four (20%) and 14 (70%) cases were test positive at day 4 - 7 and 8 - 28 days of age of neonates respectively. Most of the diseases associated with COVID-19 belonged to neonatal medicine (16,80%) and only 4 (20%) cases were associated with surgical diseases. In neonate two or more diseases coexist in same cases. Sepsis was present in 4 (20%) cases with COVID -19. Perinatal asphyxia and pneumonia both were present in 3 (15%) cases.

Conclusion: In this study the incidence of neonates with COVID-19 was 2% among the hospitalized neonates. This implies that neonates also be affected with COVID-19 and it should be properly addressed for management of neonates with COVID-19 as well as for prevention of community transmission of the disease.


Keywords: COVID-19; SARS-CoV-2; Corona Virus; Incidence of COVID-19



  1. Choi S., et al. “Epidemiology and clinical features of coronavirus disease 2019 in children”. Clinical and Experimental Pediatrics4 (2020): 125-132.
  2. Rose D., et al. “Novel Coronavirus disease (COVID-19) in newborns and infants: what we know so far”. Italian Journal of Pediatrics1 (2020): 56.
  3. Wang S., et al. “A Case Report of Neonatal 2019 Coronavirus Disease in China”. Clinical Infectious Diseases (2020): 1-5.
  4. Zhang ZJZ., et al. “Novel Coronavirus Infection in Newborn Babies Under 28 Days in China”. European Respiratory Journal6 (2020): 2000697.
  5. Dong Y., et al. “Epidemiology of COVID-19 Among Children in China”. Pediatrics6 (2020): e20200702.
  6. Aghdam MK., et al. “Novel coronavirus in a 15-day-old neonate with clinical signs of sepsis, a case report”. Infectious Diseases6 (2020): 427-429.
  7. Zeng M. “2019 novel coronavirus disease in children: an insight and the next steps forward”. Pediatric Medicine 3 (2020): 1.
  8. Piersigilli F., et al. “COVID-19 in a 26-week preterm neonate”. Lancet Child and Adolescent Health 4 (2020): 476-478.
  9. Zeng L., et al. “Neonatal Early-Onset Infection With SARS-CoV-2in 33 Neonates Born to Mothers With COVID-19 in Wuhan, China”. JAMA Pediatrics7 (2020): 722-725.
  10. Lu Q and Shi Y. “Coronavirus disease (COVID‐19) and neonate: What neonatologist need to know”. Journal of Medical Virology 92 (2020): 564-567.
  11. COVID-19 pandemic in Bangladesh.
  12. World Health Organization. Report of the WHO-China joint mission on COVID-19, 16-24 February (2020). Geneva (Switzerland): World Health Organization (2020).
  13. Chan JF., et al. “A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person to-person transmission: a study of a family cluster”. Lancet 395 (2020): 514-523.
  14. Liu W., et al. “Detection of COVID-19 in children in early January 2020 in Wuhan, China”. The New England Journal of Medicine 382 (2020): 1370-1371.
  15. Tu WX., et al. “Epidemic Update and Risk Assessment of 2019 Novel Coronavirus — China, January 28, (2020)”. China CDC Weekly 2 (2020): 83-86.
  16. The Society of Pediatrics, Chinese Medical Association the Editorial Board, Chinese Journal of Pediatrics. Recommendations for the diagnosis, prevention and control of the 2019 novel coronavirus infection in children (first interim edition). Zhonghua Er Ke Za Zhi 58 (2020): E004.
  17. Turner AJ., et al. “ACE2: from vasopeptidase to SARS virus receptor”. Trends in Pharmacological Sciences 25 (2004): 1-4.
  18. Huang C., et al. “Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China”. Lancet 10223 (2020): 497-506.
  19. Fornari F. “Vertical Transmission of Covid-19-A Systematic Review”. Journal of Pediatrics, Perinatology and Child Health 2 (2020): 007-013.
  20. Zhu H., et al. “Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia”. Translational Pediatrics 1 (2020): 51-60.
  21. Karimi-Zarchi M., et al. “Vertical Transmission of Coronavirus Disease 19 (COVID-19) from Infected Pregnant Mothers to Neonates: A Review”. Fetal and Pediatric Pathology 3 (2020): 246-250.


Citation: Maksudur Rahman.,et al. “Incidence of Corona Virus Disease 2019 (COVID-19) of Neonates at a Tertiary Care Hospital in Bangladesh". Acta Scientific Paediatrics 3.10 (2020): 11-16.


Acceptance rate33%
Acceptance to publication20-30 days
Impact Factor1.197

Indexed In

News and Events

  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is March 30, 2023.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of “Best Article of the Issue”.
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.
  • Contact US