Acta Scientific Paediatrics (ISSN: 2581-883X)

Research Article Volume 3 Issue 4

Clinico-Electroencephalographic Features of Children with Unprovoked Afebrile Seizures in Owerri, Southeast Nigeria

Christian Chukwukere Ogoke1*, Ifeanyi Innocent Ike2, Wilson Chukwuneke Igwe3 and Edmund Ndudi Ossai4

1Department of Clinical Neurophysiology/Epilepsy Monitoring Unit, Mother Healthcare Diagnostics and Hospital, Owerri, Imo State Nigeria
2Department of Paediatrics, Federal Medical Centre, Owerri, Nigeria
3Department of Paediatrics, Nnamdi Azikiwe University, Nnewi Campus and Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, Nigeria
4Department of Community Medicine, College of Health Sciences, Ebony State University, Abakiliki, Nigeria

*Corresponding Author: Christian Chukwukere Ogoke, Department of Clinical Neurophysiology/Epilepsy Monitoring Unit, Mother Healthcare Diagnostics, Nigeria.

Received: February 04, 2020; Published: March 06, 2020

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BackgroundElectroencephalography (EEG) plays a pivotal role in the diagnosis and management of epilepsies. Reports on pediatric EEGs are few in resource-poor settings due to the relative unavailability and inaccessibility of EEG facilities in these areas. Thus, only very few clinicians practicing in these settings are aware of the indications and limitations of EEG in the management of epileptic and non-epileptic paroxysmal events (NEPEs) in children. This study was therefore designed to ascertain the clinical and electroencephalographic profile of children referred for EEG in Owerri, Southeast Nigeria.

Materials and Methods: This study was a retrospective review of consecutive records of all children who did EEG at a referral centre Mother Healthcare Diagnostics & Hospital Owerri, Southeast Nigeria between January 2017 and December 2018. Relevant data from each patient’s Basic Data Sheet and EEG findings were recorded. 

Statistical analysis: Descriptive statistics was used in the analysis of results. 

Results: Out of the 115 children referred for EEG, 70(60.9%) were males, 45(39.1%) females (M:F = 1.6:1). Fifty-six (49%) of these were under 5 years of age, 72 (62.5%) had a family history of epileptic seizures and 40(35%) were neurologically abnormal. Neonates were not referred for EEG during the period under review. Four (3.5%) were referred after first unprovoked seizure, 101(87.8%) after multiple episodes and 10 (8.7%) for NEPEs. Seizure disorder (unspecified) was the provisional diagnosis in 54(47%). EEG was normal in 47 (40.9%), abnormal in 56 (48.7%) and of poor quality in 12 (10.4%). The sensitivity and specificity of a first EEG in our cohort were 62.4% and 83.3% respectively.

  Conclusions: Though half of the children utilizing EEG were under 5 years of age, no neonate was referred for EEG study. The majority of the children with epilepsy had a positive family history of epileptic seizures. Though recurrent convulsion was the most frequent reason for referral, there was little application of EEG after a first unprovoked afebrile seizure. EEG was found to be useful in our study in the management of children with epilepsy with modest sensitivity and high specificity. 

Keywords: Electroencephalography; Children; Epilepsy

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Citation

Citation: Christian Chukwukere Ogoke., et al. “Clinico-Electroencephalographic Features of Children with Unprovoked Afebrile Seizures in Owerri, Southeast Nigeria ”. Acta Scientific Paediatrics 3.4 (2020): 02-08.



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