Acta Scientific Paediatrics (ISSN: 2581-883X)

Case Report Volume 3 Issue 3

Atypical Kawasaki Disease in Adolescent Male with Liver Involvement Following Human Coronavirus OC43 Infection

Fatima Bohlok1, Zahraa Abou Hamdan1, Naima Rachini1, Sandy Rabah2, Zahraa Slim2, and Lina Mortada3*

1Department of Pediatrics, Pediatric Resident PGY4, Lebanese University, Faculty of Medical Sciences, Lebanon
2Department of Pediatrics, Pediatric Resident PGY3, Lebanese University, Faculty of Medical Sciences, Lebanon
3Pediatrician, Department of Pediatrics, Lebanese University, Faculty of Medical Sciences, Lebanon

*Corresponding Author: Lina Mortada, Pediatrician, Department of Pediatrics, Lebanese University, Faculty of Medical Sciences, Lebanon.

Received: January 21, 2020; Published: February 17, 2020

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Abstract

  Kawasaki disease is an acute febrile illness of early childhood; less than one per cent of cases are older than ten years. We report here a 13 and half years old male patient presenting with high grade fever, asthenia, myalgia, arthralgia and liver involvement followed by non-exudative conjunctivitis, skin rash on extremities plus desquamation; viral PCR panel was positive for human coronavirus HCOV-OC 43; Blood test showed elevated inflammatory markers, cholestasis and increased platelet count. After elimination of viral, bacterial and autoimmune causes we started IVIG for incomplete Kawasaki disease with good response in 24 hrs.

  Kawasaki disease is uncommon in adolescent patients, so diagnosis could be delayed increasing the risk of coronary artery anevrysm; also the cause is unknown, it may be caused by some viral illness and in our case it turn to be the human coronavirus HCOV-OC 43; liver involvement can be present in Kawasaki disease and it’s due to hepatobiliary dysfunction.

  Adolescent with Kawasaki disease may have atypical presentation, the diagnosis can be difficult; we suggest to have a high index of suspicion in evaluating adolescent patients with high grade fever of unknown origin regarding the possibility of having atypical Kawasaki and the possible coronary artery disease.

Keywords: Kawasaki Disease; Human Coronavirus OC43; Liver Involvement; Adolescent Patient; Vasculitis

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References

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Citation

Citation: Lina Mortada., et al. “Atypical Kawasaki Disease in Adolescent Male with Liver Involvement Following Human Coronavirus OC43 Infection”. Acta Scientific Paediatrics 3.3 (2020): 01-03.



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