Acta Scientific Paediatrics (ISSN: 2581-883X)

Research Article Volume 3 Issue 2

The Efficacy and Safety of Single Daily Dosing Ceftriaxone and Metronidazole vs the Triple Antibiotic Regimen for Complicated Appendicitis in Children

D Yardeni1*, R Billik4, L Siplovich1, B Kawar1, SE Golladay1, I Rosine1, M Zebidat1, H Polla1, Z Gwetta1, Y Ochayon1, A Pressman1, V Sacran2 and D Miron3

1Pediatric Surgery Department Ha’emek Medical Center, Afula, Israel
2Pediatric Department A, Ha’emek Medical Center, Afula, Israel
3Pediatric Department B, Ha’emek Medical Center, Afula, Israel
4Pediatric Surgery Department, Safra Children Hospital, Sheba Medical Center, Israel

*Corresponding Author: D Yardeni, Pediatric Surgery Department Ha’emek Medical Center, Afula, Israel.

Received: December 16, 2019; Published: January 22, 2020


  Triple antibiotic therapy using ampicillin, gentamicin, and metronidazole (AGM) providing broad-spectrum coverage of gram-positive, gram-negative, and anaerobic bacteria, has been the standard treatment of complicated appendicitis in children.

Keywords:Ceftriaxone and Metronidazole; Safety; AGM; Appendicitis



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Citation: D Yardeni., et al. “The Efficacy and Safety of Single Daily Dosing Ceftriaxone and Metronidazole vs the Triple Antibiotic Regimen for Complicated Appendicitis in Children”. Acta Scientific Paediatrics 3.2 (2020): 01-06.

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