Paul Hagedoorn¹, Richard Dekhuijzen², Johan Kooistra³ and Robert Janknegt⁴*

¹technologist Inhalation, Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, The Netherlands
²Pulmonologist, Radboud University Medical Center, Nijmegen, The Netherlands
³BENU Pharmacies, Maarssen, The Netherlands
⁴Hospital Pharmacist, Clinical Pharmacologist Sittard, The Netherlands

*Corresponding Author: Robert Janknegt, Hospital Pharmacist, Clinical Pharmacologist Sittard, The Netherlands.

Received: December 13, 2021 Published: December 31, 2021

Abstract

Valved inhalation chambers are important instruments to increase the available dose of pressurized metered dose inhalers, in this study inhalation chambers are compared by means of the System of Objectified Judgement Analysis (SOJA) method. The SOJA method is a model for rational drug selection. The relevant selection criteria for inhalation chambers are defined and judged by a panel of experts and each selection criterion is given a relative weight. The following inhalation chambers were included: Aerochamber, Inspirachamber, Optichamber, Volumatic and Vortex. Selection criteria were: Transparancy, Feedback system in case of too forceful inhalation, Antistatic properties, Dose delivery, Availability of mouth masks, Easy to carry, Suitability for children and inclusion in Summaries of Product Characteristics of metered dose inhalers. Aerochamber showed by far the highest score. If performed well on all selection criteria. Vortex and Optichamber also performed well. Volumatic showed the lowest score.

Keywords: Asthma; COPD; Valved Holding; Aerochamber

References

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Citation

Citation: Robert Janknegt., et al. “Rational Selection of Valved Holding Chambers in the Treatment of COPD or Asthma by Means of the System of Objectified Judgement Analysis". Acta Scientific Pharmacology 3.1 (2022): 46-53.

Copyright

Copyright: © 2022 Robert Janknegt., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.