Kunal Joon*

MK Franklin Shaju¹, S Cathrine² and J Afrin Sithara³*

*Corresponding Author: J Afrin Sithara, MPT in Neurology, RVS College of Physiotherapy, The Tamil Nadu Dr. M.G.R. University, India.

Received: May 08, 2026; Published: May 31, 2026

Abstract

Cognitive ability decline can be preserved NAD plus supplementation or it’s precursor can be used. The NAD plus can prevent vascular dementia, age related cognitive decline. As NAD plus decline cause decline in the cognitive ability and increased dementia and even it can lead to Alzheimer’s disease and even symptoms Parkinson disease.

Keywords: Alzheimer’s Disease; NAD Plus; NADH Plus H Supplementation; Neuroprotection

References

1. Wimalasundera N and Stevenson VL. “Cerebral palsy”. Practice Neurology3(2016): 184-194.v
2. Dewar R., et al. “Exercise interventions improve postural control in children with cerebral palsy: a systematic review”. Developmental Medicine & Child Neurology6 (2015): 504-520.
3. DeLuca SC., et al. “Constraint-induced movement therapy (CIMT) for young children with cerebral palsy: effects of therapeutic dosage”. Journal of Pediatric Rehabilitation Medicine2 (2012): 133-142.
4. Pool D., et al. “Locomotor and robotic assistive gait training for children with cerebral palsy”. Developmental Medicine & Child Neurology3 (2021): 328-335.
5. Jung SH., et al. “Does virtual reality training using the Xbox Kinect have a positive effect on physical functioning in children with spastic cerebral palsy? A case series”. Journal of Pediatric Rehabilitation Medicine2 (2018): 95-101.
6. Sah AK., et al. “Effects of Task-oriented Activities Based on Neurodevelopmental Therapy Principles on Trunk Control, Balance, and Gross Motor Function in Children with Spastic Diplegic Cerebral Palsy: A Single-blinded Randomized Clinical Trial”. Journal of Pediatric Neuroscience3 (2019): 120-126.
7. Karadağ-Saygı E and Giray E. “The clinical aspects and effectiveness of suit therapies for cerebral palsy: A systematic review”. Turkish Journal of Physical Medicine and Rehabilitation1 (2019): 93-110.
8. Vitrikas K., et al. “Cerebral Palsy: An Overview”. American Family Physician4 (2020): 213-220.
9. Te Velde A., et al. “Neurodevelopmental Therapy for Cerebral Palsy: A Meta-analysis”. Pediatrics6 (2022): e2021055061.
10. Khanna S., et al. “Neurodevelopmental Treatment in Children With Cerebral Palsy: A Review of the Literature”. Cureus12 (2023): e50389.
11. Ungureanu A., et al. “Balance Rehabilitation Approach by Bobath and Vojta Methods in Cerebral Palsy: A Pilot Study”. Children10 (2022): 1481.
12. Ramey SL., et al. “Constraint-Induced Movement Therapy for Cerebral Palsy: A Randomized Trial”. Pediatrics 5 (2021): e2020033878.
13. Hoare BJ., et al. “Constraint-induced movement therapy in children with unilateral cerebral palsy”. Cochrane Database System Review4(2019): CD004149.
14. Volpini M., et al. “Clinical effects of assisted robotic gait training in walking distance, speed, and functionality are maintained over the long term in individuals with cerebral palsy: a systematic review and meta-analysis”. Disability and Rehabilitation19(2022): 5418-5428.
15. Cortés-Pérez I., et al. “Efficacy of Robot-Assisted Gait Therapy Compared to Conventional Therapy or Treadmill Training in Children with Cerebral Palsy: A Systematic Review with Meta-Analysis”. Sensors 24(2022): 9910.
16. Moll F., et al. “Use of Robot-Assisted Gait Training in Pediatric Patients with Cerebral Palsy in an Inpatient Setting-A Randomized Controlled Trial”. Sensors24 (2022): 9946.
17. Klobucká S., et al. “Cost-effectiveness analysis of robot-assisted gait training in patients with bilateral spastic cerebral palsy”. Cost-Effective Resource Allocation1 (2023): 60.
18. Bailes AF., et al. “Changes in two children with cerebral palsy after intensive suit therapy: a case report”. Pediatric Physical Therapy1 (2010): 76-85.
19. Belizón-Bravo N., et al. “Effects of Dynamic Suit Orthoses on the Spatio-Temporal Gait Parameters in Children with Cerebral Palsy: A Systematic Review”. Children 11 (2021): 1016.
20. Buccino G., et al. “Improving upper limb motor functions through action observation treatment: a pilot study in children with cerebral palsy”. Developmental Medicine & Child Neurology 9 (2012): 822-828.
21. Souto DO., et al. “Motor imagery in children with unilateral cerebral palsy: a case-control study”. Developmental Medicine & Child Neurology12 (2020): 1396-1405.
22. Montoro-Cárdenas D., et al. “Nintendo Wii Balance Board therapy for postural control in children with cerebral palsy: a systematic review and meta-analysis”. Developmental Medicine & Child Neurology11 (2021): 1262-1275.
23. Ziab H., et al. “Effectiveness of virtual reality training compared to balance-specific training and conventional training on balance and gross motor functions of children with cerebral palsy: A double blinded randomized controlled trial”. Journal of Pediatric Rehabilitation Medicine3 (2024): 353-368.
24. Perez-Carcamo J., et al. “Effectiveness of Non-Immersive Virtual Reality on Gross Motor Function, Balance, and Functional Independence in Children with Cerebral Palsy: A Systematic Review with Meta-Analysis”. Journal of Clinical Medicine21 (2025): 7582.
25. Cortés-Pérez I., et al. “Dual-Task Training Interventions for Cerebral Palsy: A Systematic Review and Meta-Analysis of Effects on Postural Balance and Walking Speed”. Medicina (Mex)8 (2025): 1415.
26. Tekeş SEÖ., et al. “Robot-assisted gait training in children with cerebral palsy: a randomized comparative study”. Developmental Neurorehabilitation4-5 (2025): 163-72.
27. Martin-Moreno G., et al. “Constraint-Induced Movement Therapy Versus Bimanual Training to Improve Upper Limb Function in Cerebral Palsy: A Systematic Review and Meta-Analysis of Follow-Ups”. Children 12(6 (2025): 804.

Citation

Citation: J Afrin Sithara., et al. “Contemporary, Novel and Modern Approaches in the Neurorehabilitation of Cerebral Palsy: A Narrative Review". Acta Scientific Neurology 9.6 (2026): 16-23.

Copyright

Copyright: ©2026 J Afrin Sithara., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.