Acta Scientific Neurology (ASNE) (ISSN: 2582-1121)

Case Report Volume 9 Issue 1

Complex Presentation of Acute Ischemic Stroke with Small Haemorrhagic Foci and Cranial Nerve Involvement in the Background of Diabetes, Hypertension, and Ischemic Heart Disease

Animesh Das* and E Satheesh Kumar

Department of Pharmacy Practice RR College of Pharmacy Chikkabanavara, Bangalore, 560090, Karnataka, India

*Corresponding Author: Animesh Das, Department of Pharmacy Practice RR College of Pharmacy Chikkabanavara, Bangalore, 560090, Karnataka, India.

Received: December 18, 2025; Published: December 26, 2025

Abstract

This case describes a patient who developed an acute stroke in the presence of several health problems. Sudden onset of dizziness followed by a fall with head injury. After this, he developed slurred speech, weakness of the left arm, and deviation of the mouth to the left. Symptoms appeared suddenly, did not progress, and there was no loss of consciousness. He was admitted to the neurology department for evaluation. On admission, investigations showed haemoglobin 13.2 g/dL, white blood cell count 9200, and platelets 3.19 lakh. However, blood clotting studies showed increased prothrombin time of 16.3 and INR of 12.6 on some days, indicating delayed clotting. His medical history revealed hypertension for five years, type 2 diabetes mellitus, and ischemic heart disease for ten years. He had undergone coronary angioplasty earlier and was taking medicines like enalapril, metformin, glimepiride, atorvastatin, and clopidogrel. He had quit smoking ten years ago after smoking 5–10 cigarettes daily for 15 years. He did not consume alcohol. During admission, he was treated conservatively as advised by neurosurgery, cardiology, and ophthalmology teams. Antiplatelet medicines were stopped due to the presence of intracranial bleeding. He received intravenous antibiotics (ceftriaxone), stomach protection (pantoprazole), an antiemetic (ondansetron), mannitol to reduce brain swelling, vitamin injections, and insulin for blood sugar control. Other medicines included bisoprolol, enalapril, atorvastatin, modafinil, and baclofen. Supportive care included physiotherapy for limb and speech recovery, restricted salt intake below 2 g/day, and limited fluid intake below 1.2 L/day. This case highlights the role of careful conservative management and the importance of long-term rehabilitation in a patient with multiple risk factors such as hypertension, diabetes, and heart disease.

Keywords:Ischemic Stroke; Hypertension; Coronary Angioplasty; Diabetes Mellitus

References

  1. K Burson., et al. “A Focal Pontine Infarct Presenting as Unilateral Facial Nerve Paralysis”. Cureus (2020).
  2. R She., et al. “Comorbidity in patients with first-ever ischemic stroke: Disease patterns and their associations with cognitive and physical function”. Frontiers in Aging Neurosciences 14 (2022).
  3. H Liu., et al. “Effect of Comorbidity Assessed by the Charlson Comorbidity Index on the Length of Stay and Mortality Among Immobile Hemorrhagic Stroke Patients Younger Than 50 Years”. Frontiers in Neurology 11 (2020).
  4. R Saini., et al. “Serum Vitamin B12 Levels in Patients of Ischaemic Stroke: A Cross-Sectional Study” (2023).
  5. K I Gallacher., et al. “Multimorbidity in Stroke”. Lippincott Williams and Wilkins (2019).
  6. D M Kelly and P M Rothwell. “Impact of multimorbidity on risk and outcome of stroke: Lessons from chronic kidney disease”. SAGE Publications Inc (2021).
  7. V Atam., et al. “Serum Vitamin B12 Levels as a Risk Factor and Prognostic Marker in Patients With Acute Ischemic Stroke at a Tertiary Care Center in Northern India: A Case-Control Study”. Cureus (2024).
  8. K Phipps., et al. “Pontine Infarct Camouflaged as Bell’s Palsy”. Journal of Neurology Research1-2 (2019): 14-17.
  9. P Kumar., et al. “Neurocysticercosis With Internal Carotid Artery and Middle Cerebral Artery Vasculitis and Stenosis”. Cureus (2022).
  10. C Asavaaree., et al. “Malignant middle cerebral artery infarction due to hyponatremia following traumatic brain injury: A case report”. American Journal of Case Reports 20 (2019): 258-262.
  11. S Biradar., et al. “A Case report of ischaemic infarct secondary to vitamin B 12 deficiency induced hyperhomocystenaemia”. RGUHS Journal of Medical Sciences1 (2019).

Citation

Citation: Animesh Das and E Satheesh Kumar. “Complex Presentation of Acute Ischemic Stroke with Small Haemorrhagic Foci and Cranial Nerve Involvement in the Background of Diabetes, Hypertension, and Ischemic Heart Disease".Acta Scientific Neurology 9.1 (2026): 21-26.

Copyright

Copyright: © 2026 Animesh Das and E Satheesh Kumar. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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