Acta Scientific Neurology (ASNE) (ISSN: 2582-1121)

Case Report Volume 8 Issue 9

Acute Ischemic Stroke as a First Manifestation of Severe Iron Deficiency Anemia in a Toddler: A Case Report

Shria Sadhu1*, Taqwa Drdir1, Madiha Fatima1, Eman Taryam2 and Aman Sohal3

1Department of General Pediatrics, Al Qassimi Women’s and Children’s Hospital, UAE
2Department of Pediatric Hematology Oncology, Al Jalila Children's Hospital
3Department of Pediatrics Neurology, Al Qassimi Women’s and Children’s Hospital, UAE

*Corresponding Author: Shria Sadhu, General Pediatrics, Al Qassimi Women and Children Hospital, Sharjah, United Arab Emirates.

Received: July 10, 2025; Published: August 04, 2025

Abstract

Iron deficiency anemia (IDA) remains the most prevalent micronutrient deficiency in children globally, often presenting with symptoms such as pale skin, reduced exercise tolerance, poor appetite, increased susceptibility to infections, and developmental delays. Among its numerous effects, the most concerning are those on the developing neurocognitive system. While its association with thromboembolic complications, particularly arterial ischemic stroke (AIS), is considered rare and often overlooked in pediatric populations, emerging evidence suggests a potential link. We present a rare case of a previously healthy toddler who was diagnosed with ischemic stroke due to a large vessels occlusion (Left Internal Carotid Artery) as the initial manifestation of severe IDA. This case highlights the importance of considering IDA as a possible underlying etiology in pediatric stroke presentations.

Keywords: Acute Ischemic Stroke; Severe Iron; Anemia; Toddler

References

  1. Munot P., et al. “Severe iron deficiency anaemia and ischaemic stroke in children”. Archives of Disease in Childhood 96 (2011): 276-279.
  2. Hartfield DS., et al. “Iron deficiency: a cause of stroke in infants and children”. Pediatric Neurology 1 (1997): 50-53.
  3. Gonzalez Vincent B., et al. “Iron Deficiency Anemia Presenting as Ischemic Stroke in Pediatric Patient”. Clinical Pediatrics7 (2024): 1017-1020.
  4. Eric Nathan Laber and Damian A Laber. “Association between Iron Deficiency Anemia and Thrombosis, a Population Based Study”. Blood1 (2023): 5232-5232.
  5. Kalff Hannah., et al. “Iron deficiency anemia and thrombosis risk in children-revisiting an old hypothesis”. Frontiers in Pediatrics 10 (2022):
  6. Ciacciarelli A., et al. “The prognostic role of iron deficiency in acute ischemic stroke patients: A prospective multicentric cohort study”. The Journal of the Neurological Sciences  469 (2023):

Citation

Citation: Shria Sadhu. “Acute Ischemic Stroke as a First Manifestation of Severe Iron Deficiency Anemia in a Toddler: A Case Report".Acta Scientific Neurology 8.9 (2025): 03-06.

Copyright

Copyright: © 2025 Shria Sadhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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