Functional Electrical Stimulation Cycling: A Comprehensive Review of Contemporary Evidence and Recent Advancements
Brammatha A1,2*, MK Franklin Shaju3 and Kannabiran B4
1Ph.D. Scholar, RVS College of Physiotherapy, The Tamil Nadu Dr. M. G. R. Medical University, Chennai, India
2Professor, KMCH College of Physiotherapy, Coimbatore, The Tamil Nadu Dr. M. G. R. Medical University, Chennai, India
3Principal and Ph.D. Guide, RVS College of Physiotherapy. The Tamil Nadu Dr. M. G. R. Medical University, Chennai, India
4Professor and Co Guide, RVS College of Physiotherapy. The Tamil Nadu Dr. M. G. R. Medical University, Chennai, India
*Corresponding Author: Brammatha A, Professor, KMCH College of Physiotherapy, Coimbatore, Affiliated to The Tamil Nadu Dr. M. G. R. Medical University, Chennai, India.
Received:
February 28, 2025; Published: March 13, 2025
Abstract
Therapeutic Functional Electrical Stimulation Cycling (FESC) involves the application of Functional Electrical Stimulation (FES) that is synchronized with the cycling motion, thus facilitating a harmonized activation of the lower limb musculature that mirrors the cyclical movements associated with locomotion. Electrical impulses are transmitted through electrodes strategically placed on the epidermis over the designated muscle groups.
Post-stroke lower limb impairments often manifest as muscle weakness, irregular muscle coactivation, and compromised joint torque coupling during gait and posture, which can diminish the flexibility of the cortical motor network, ultimately resulting in restricted motor behavior and impaired walking functionality. The repetitive characteristics of the cycling exercise are believed to foster motor learning while enhancing muscle strength, endurance, and coordination. In terms of functional outcomes, FES cycling has demonstrated benefits in enhancing overall mobility and daily living activities. Clinical trials have reported improvements in gait speed, symmetry and balance which can translate to better performance in tasks such as walking and standing. This paper reviews the evidences for lower limb FES cycling in stroke population, mechanisms of action, implications for clinical practice and technological advancements.
Keywords: Functional Electrical Stimulation Cycling; FESC; FES; Lower Limb Cycling; Stroke; Hemiplegia; Physiotherapy
References
- Tan Kay Sin., et al. “Stroke in Asia”. Cerebrovascular Diseases Extra 14.1 (2024): 58-75.
- Gorthi Sankar P and Divyani Garg. “Stroke Epidemiology among Young Persons in India: Every Step Counts”. Annals of Indian Academy of Neurology 25.1 (2022): 1.
- Kamalakannan Sureshkumar., et al. “Incidence and prevalence of stroke in India: A systematic review”. The Indian Journal of Medical Research 146.2 (2017): 175-185.
- Venkatasubramanian Narayanaswamy., et al. “Stroke Epidemiology in South, East, and South-East Asia: A Review”. Journal of Stroke 19.3 (2017): 286-294.
- Frenkel-Toledo Silvi., et al. “Stroke Lesion Impact on Lower Limb Function”. Frontiers in Human Neuroscience (2017).
- Hsiao Hao-Yuan., et al. “Biomechanical control of paretic lower limb during imposed weight transfer in individuals post-stroke”. Journal of NeuroEngineering and Rehabilitation 17.1 (2017).
- Tamaya Van Criekinge., et al. “Trunk biomechanics during walking after sub-acute stroke and its relation to lower limb impairments”. Clinical Biomechanics 75 (2020): 105013.
- Sánchez Natalia., et al. “Lower Extremity Motor Impairments in Ambulatory Chronic Hemiparetic Stroke: Evidence for Lower Extremity Weakness and Abnormal Muscle and Joint Torque Coupling Patterns”. Neurorehabilitation and Neural Repair 31. (2017): 814-826.
- Rozanski Gabriela M., et al. “Lower limb muscle activity underlying temporal gait asymmetry post-stroke”. Clinical Neurophysiology 131.8 (2020): 1848-1858.
- Liu Wan-Ju., et al. “Impacts of Stroke on Muscle Perceptions and Relationships with the Motor and Functional Performance of the Lower Extremities”. Sensors 21.14 (2021): 4740.
- Luo Haizhen and Jie Luo. “Evaluating the Intra-limb Coordination during Gait in Hemiplegia”. 2018 IEEE International Conference on Cyborg and Bionic Systems (CBS) (2018).
- Alvarenga Maria T., et al. “Deficits in dynamic balance were the motor impairments that best explained limitations in community ambulation after stroke”. European Journal of Physical and Rehabilitation Medicine 59.2 (2023).
- Liu Chang., et al. “Impairments in the mechanical effectiveness of reactive balance control strategies during walking in people post-stroke”. Frontiers in Neurology (2022).
- Gorst Terry., et al. “Foot and ankle impairments affect balance and mobility in stroke (FAiMiS): the views and experiences of people with stroke”. Disability and Rehabilitation 38.6 (2015): 589-596.
- Menezes K., et al. “Lower-limb motor coordination is significantly impaired in ambulatory people with chronic stroke: A cross-sectional study”. Journal of Rehabilitation Medicine 49.4 (2017): 322-326.
- Cruz Theresa Hayes., et al. “Biomechanical impairments and gait adaptations post-stroke: Multi-factorial associations”. Journal of Biomechanics 42.11 (2009): 1673-1677.
- Marquez-Chin Cesar and Milos R Popovic. “Functional Electrical Stimulation Therapy for Restoration of Motor Function after Spinal Cord Injury and Stroke: A Review”. BioMedical Engineering OnLine 19.1 (2020).
- Liberson WT., et al. “Functional electrotherapy: stimulation of the peroneal nerve synchronized with the swing phase of the gait of hemiplegic patients”. Archives of Physical Medicine and Rehabilitation vol. 42 (1961): 101-105.
- Kapadia Naaz., et al. “Functional Electrical Stimulation Therapy for Retraining Reaching and Grasping after Spinal Cord Injury and Stroke”. Frontiers in Neuroscience 14.718 (2020).
- Muhammad Ahmed Khan., et al. “A Systematic Review on Functional Electrical Stimulation Based Rehabilitation Systems for Upper Limb Post-Stroke Recovery”. Frontiers in Neurology 14 (2023).
- Rouse Courtney A., et al. “FES Cycling in Stroke: Novel Closed-Loop Algorithm Accommodates Differences in Functional Impairments”. IEEE Transactions on Biomedical Engineering 67.3 (2020): 738-749.
- Peri Elisabetta., et al. “Can FES-Augmented Active Cycling Training Improve Locomotion in Post-Acute Elderly Stroke Patients?” European Journal of Translational Myology 26.3 (2017): 6063.
- Holzapfel Simon D., et al. “Acute Effects of Assisted Cycling Therapy on Post-Stroke Motor Function: A Pilot Study”. Rehabilitation Research and Practice 2019 (2019): 1-10.
- Sun Jinping., et al. “Electrical Stimulation of the Motor Cortex or Paretic Muscles Improves Strength Production in Stroke Patients: A Systematic Review and Meta-Analysis”. PM and R: the Journal of Injury, Function, and Rehabilitation 13.2 (2021): 171-179.
- Ha Sun-Young., et al. “Ankle exercise with functional electrical stimulation affects spasticity and balance in stroke patients”. Journal of Exercise Rehabilitation 16.6 (2020): 496-502.
- Shi Jiajie. “Current Technical Study on Functional Electrical Simulation for Stroke Patients”. Highlights in Science Engineering and Technology 74 (2023): 474-479.
- Hwang Sujin and Chiang-Soon Song. “Rehabilitative Effects of Electrical Stimulation on Gait Performance in Stroke Patients: A Systematic Review with Meta-Analysis”. NeuroRehabilitation (2024): 1-13.
- Aaron Stacey E., et al. “FES-Assisted Cycling Improves Aerobic Capacity and Locomotor Function Post-CVA”. Medicine and Science in Sports and Exercise 50.3 (2018): 400-406.
- Lutokhin GM., et al. “Application of Exoskeleton with Functional Electrostimulation for Rebalancing of Patients in Acute and Early Recovery Periods of Ischemic Stroke”. Problems of Balneology Physiotherapy and Exercise Therapy 100.5 (2023): 5-5.
- Bao Shi-chun., et al. “Rewiring the Lesioned Brain: Electrical Stimulation for Post-Stroke Motor Restoration”. Journal of Stroke 22.1 (2020): 47-63.
- Li Le., et al. “Immediate Effects of Functional Electrical Stimulation-Assisted Cycling on the Paretic Muscles of Patients with Hemiparesis after Stroke: Evidence from Electrical Impedance Myography”. Frontiers in Aging Neuroscience 14 (2022).
- Milosevic Matija., et al. “Cortical Re-Organization after Traumatic Brain Injury Elicited Using Functional Electrical Stimulation Therapy: A Case Report”. Frontiers in Neuroscience 15 (2021): 693861.
- Gandolla Marta., et al. “The Neural Correlates of Long-Term Carryover following Functional Electrical Stimulation for Stroke”. Neural plasticity 2016 (2016): 4192718.
- Bao Shi-Chun., et al. “Pathway-specific modulatory effects of neuromuscular electrical stimulation during pedaling in chronic stroke survivors”. Journal of NeuroEngineering and Rehabilitation 16.1 (2016).
- Hunt KJ., et al. “On the efficiency of FES cycling: A framework and systematic review”. Technology and Health Care 20.5 (2012): 395-422.
- Wang Wenyuan., et al. “FES Cycling System in Rehabilitation Engineering: A Survey”. Lecture Notes in Electrical Engineering (2024): 532-541.
- Peri Elisabetta., et al. “Can FES-Augmented Active Cycling Training Improve Locomotion in Post-Acute Elderly Stroke Patients?” European Journal of Translational Myology 26.3 (2016): 6063.
- Chia-Ying., et al. “The Effect and Dose-Response of Functional Electrical Stimulation Cycling Training on Spasticity in Individuals with Spinal Cord Injury: A Systematic Review with Meta-Analysis”. Frontiers in Physiology (2021).
- Deichsel Adrian., et al. “Study designs, levels of evidence, and scientific bias”. Arthroskopie 37.4 (2024): 224-231.
- Wagner Rodrigues Galvão., et al. “Cycling Using Functional Electrical Stimulation Therapy to Improve Motor Function and Activity in Post-Stroke Individuals in Early Subacute Phase: A Systematic Review with Meta-Analysis”. Biomedical Engineering Online 23.1 (2024).
- Murillo Frazão., et al. “A Systematic Review and Meta-Analysis of Physiological and Clinical Effects of FES-Cycling”. Archives of Physical Medicine and Rehabilitation (2024).
- Fang Yu., et al. “Optimization of electrical stimulation for the treatment of lower limb dysfunction after stroke: A systematic review and Bayesian network meta-analysis of randomized controlled trials”. PLoS ONE 18.5 (2024): e0285523.
- Barclay Alison., et al. “The Effects of Cycling Using Lower Limb Active Passive Trainers in People with Neurological Conditions: A Systematic Review”. International Journal of Therapy and Rehabilitation 29.6 (2022): 1-21.
- Mahmoudi Zeinab., et al. “The Effects of Electrical Stimulation of Lower Extremity Muscles on Balance in Stroke Patients: A Systematic Review of Literatures”. Journal of Stroke and Cerebrovascular Diseases 30.8 (2021): 105793.
- Ambrosini Emilia., et al. “Does Cycling Induced by Functional Electrical Stimulation Enhance Motor Recovery in the Subacute Phase after Stroke? A Systematic Review and Meta-Analysis”. Clinical Rehabilitation 34.11 (2020): 1341-1354.
- Shariat Ardalan., et al. “The effects of cycling with and without functional electrical stimulation on lower limb dysfunction in patients post-stroke: A systematic review with meta-analysis”. Neurorehabilitation 44.3 (2019): 389-412.
- Ahmad., et al. “Closed-Loop Functional Electrical Stimulation (FES) - Cycling Rehabilitation with Phase Control Fuzzy Logic for Fatigue Reduction Control Strategies for Stroke Patients”. SINERGI 28.1 (2023): 63-63.
- Alashram AR., et al. “Changes in spasticity following functional electrical stimulation cycling in patients with spinal cord injury: A systematic review”. The Journal of Spinal Cord Medicine 45.1 (2020): 10-23.
- Singleton C., et al. “Functional Electrical Stimulation (FES) for Children and Young People with Cerebral Palsy”. Paediatrics and Child Health 29.11 (2016): 498-502.
- Scally Jennifer B., et al. “Evaluating Functional Electrical Stimulation (FES) Cycling on Cardiovascular, Musculoskeletal and Functional Outcomes in Adults with Multiple Sclerosis and Mobility Impairment: A Systematic Review”. Multiple Sclerosis and Related Disorders 37 (2020): 101485.
Citation
Copyright