Acta Scientific Neurology (ASNE) (ISSN: 2582-1121)

Mini Review Volume 6 Issue 10

Bone Health in Patients with Pituitary and Hypothalamic Tumors, Importance of Prevention of Bone Fracture

Ichiro Nakazato1,2, Akira Matsuno2,3*, Keisuke Onoda3, Takayuki Shiomi4 and Kenichi Oyama2

1Basic Medical Sciences, International University of Health and Welfare, Graduate School of Medicine, Narita City, Chiba, Japan
2Department of Neurosurgery, International University of Health and Welfare Mita Hospital, Minato-ku, Tokyo, Japan
3Department of Neurosurgery, International University of Health and Welfare Narita Hospital, Narita City, Chiba, Japan
4Department of Pathology, International University of Health and Welfare Narita Hospital, Narita City, Chiba, Japan

*Corresponding Author: Akira Matsuno, Department of Neurosurgery, International University of Health and Welfare Mita Hospital, Minato-ku, Tokyo, Japan.

Received: September 04, 2023; Published: September 07, 2023

Abstract

Pituitary or hypothalamic disorders including hypopituitarism, Cushing disease, and hyperprolactinemia are major causes of osteoporosis. Patients with pituitary or hypothalamic lesions have tendency of association of hypopituitarism in both preoperative and postoperative endocrinological assessment. Growth hormone deficiency is also one of the considerable risks of osteopenia. Thus, in surgery for pituitary or hypothalamic lesions, preservation of pituitary function and postoperative appropriate hormone replacement therapy are required.

Keywords: Bone Health; Patients; Pituitary; Hypothalamic Tumors Bone Fracture

References

  1. MazziottiG., et al. “Pituitary diseases and bone”. Endocrine Reviews 39 (2018): 440-488.
  2. Auriemma RS., et al. “Approach to the Patient with Prolactinoma”. Journal of Clinical Endocrinology and Metabolism (2023): 174.
  3. Okinaga H., et al. “High risk of osteopenia and bone derangement in postsurgical patients with craniopharyngiomas, pituitary adenomas and other parasellar lesions”. Endocrine Journal 52 (2005): 751-756.
  4. Dineen R., et al. “The contribution of serum cortisone and glucocorticoid metabolites to detrimental bone health in patients receiving hydrocortisone therapy”. BMC Endocrine Disorders 20 (2020): 154.
  5. Holmes SJ Sasaki M., et al. “Reduced bone mineral density in patients with adult-onset growth hormone deficiency”. Journal of Clinical Endocrinology and Metabolism 78 (1994): 669-674.
  6. Sasaki M., et al. “Preoperative elevated serum growth hormone is preventive of osteopenia in postsurgical patients with pituitary somatotroph adenomas: comparison with clinically non-functioning adenomas”. Endocrinologist 19 (2009): 208-210.

Citation

Citation: Akira Matsuno., et al. “Bone Health in Patients with Pituitary and Hypothalamic Tumors, Importance of Prevention of Bone Fracture". Acta Scientific Neurology 6.10 (2023): 09-10.

Copyright

Copyright: © 2023 Akira Matsuno., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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