Covid-19 Infection and Meningoencephalitis in Pregnancy: A Case at the Douala Gynaeco-obstetric and Pediatric Hospital of Douala
Djomo Tamchom Dominique1,5, Gueumekane Bila Lamou Eric1,3*, Onana Yannick1,2, Kamdem Modjo Diane Estelle1, Habiba Noura Ben Moussa1, Ngaba Guy Pascal1,3 and Mboudou Emile Telesphore1,3,4
1Douala Gynaeco-Obstetric and Pediatric Hospital, Cameroon
2Faculty of Medicine and Biomedical Sciences, University of Ngaoundéré, Cameroon
3Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Cameroon
4Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Cameroon
5Faculty of Medicine, Free University of Brussels, Cameroon
6Faculty of Health Sciences, University of Buea, Cameroon
*Corresponding Author: Gueumekane Bila Lamou Eric, Douala Gynaeco-Obstetric and Pediatric Hospital, Cameroon.
June 25, 2021; Published: August 07, 2021
A 25-year-old expecting patient, G4P3 003, with no known pathological history, was referred to us for status epilepticus progressing for 2 days, on a pregnancy of 34 weeks of amenorrhea + 5 days, in a context of unspecified fever, without an increase in blood pressure (BP = 104/63 mmHg). The physical examination shows stiff meninges and post-critical coma with an estimated Glasgow score of 8/15 modified by aphasia, and vaginal examination is normal.
The biological assessment made on admission shows a normal blood count, ketonuria at 150 mg (+++) without proteinuria on the urine test strip. D-dimers, LDH and procalcitonin are high. An emergency obstetric ultrasound and brain CT scan are normal. Real-time PCR on a nasopharyngeal swab for COVID-19, routinely performed on admission in the context of a pandemic, revealed the presence of SARS-COV-2 RNA. The diagnostic hypotheses put forward were non-typical eclampsia, cerebral thrombophlebitis or meningoencephalitis in an active pregnancy associated with the COVID-19 disease. The management consisted of an emergency cesarean, a treatment protocol for COVID-19, an anticonvulsant and physiotherapy. The clinical progression was very satisfactory after 7 days. It is important to draw the attention of practitioners to the polymorphism of COVID-19 in vulnerable areas such as that of pregnant women.
Keywords: COVID-19; Meningoencephalitis; Pregnancy
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© 2021 Gueumekane Bila Lamou Eric., et al.
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