Milanko Maksić^1,2, Tamara Đurić-Kun³, Vladimir Keča¹, Snježana Milićević^1,3, Dragan Milošević^1,4, Aleksandar Košpić²*, Momir Bobar² and Lazar B Davidović^5,6

¹Faculty of Medicine, University of Banja Luka, Banja Luka, Republika Srpska, Bosnia and Herzegovina ²Clinic for Vascular Surgery, University Clinical Center of the Republic of Srpska, Banja Luka, Republika Srpska, Bosnia and Herzegovina ³Clinic for Urology, University Clinical Center of the Republic of Srpska, Banja Luka, Republika Srpska, Bosnia and Herzegovina ⁴Clinic for Anesthesiology and Intensive Care, University Clinical Center of the Republic of Srpska, Banja Luka, Republika Srpska, Bosnia and Herzegovina ⁵Faculty of Medicine, University of Belgrade, Belgrade, Serbia ⁶Clinic for Vascular and Endovascular Surgery, University Clinical Center of Serbia, Belgrade, Serbia

*Corresponding Author: Aleksandar Košpić, Clinic for Vascular Surgery, University Clinical Center of the Republic of Srpska, Banja Luka, Bosnia and Herzegovina.

Received: September 09, 2026; Published: October 06, 2026

Renal cell carcinoma (RCC) is the most common malignant tumor involving the inferior vena cava (IVC), and intraluminal tumor thrombus is associated with poor prognosis without surgical treatment. We retrospectively analyzed five consecutive patients with RCC and IVC involvement treated between 2020 and 2026. One patient had Mayo level 0 thrombus, three had level I, and one had level II. All patients underwent radical nephrectomy with tumor thrombectomy and IVC reconstruction, including lateral venorrhaphy (3), bovine pericardial patch angioplasty (1), and suprarenal IVC replacement with an 18-mm Dacron graft (1). There were no major postoperative complications or 30-day mortality. During a mean follow-up of 34 months (range, 3–60), no local recurrence or distant metastases were observed and overall survival was 100%. Radical surgery performed by an experienced multidisciplinary team can achieve favorable early and mid-term outcomes in carefully selected patients with RCC and IVC invasion.

Keywords: Renal Cell Carcinoma; Inferior Vena Cava; Tumor Thrombus; Mayo Classification; IVC Reconstruction

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Citation

Citation: Aleksandar Košpić., et al. “Surgical Treatment of Renal Cell Carcinoma with Inferior Vena Cava Invasion". Acta Scientific Medical Sciences 10.10 (2026): 84-90.

Copyright

Copyright: © 2026 Aleksandar Košpić., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.