EG Tumashov¹, AV Troitsky²* and TN Bystrova²

¹Kosmeliya LTD, Novosibirsk, Russia
²Federal Research Center for Fundamental and Translational Medicine, Novosibirsk, Russia

*Corresponding Author: AV Troitsky, Federal Research Center for Fundamental and Translational Medicine, Novosibirsk, Russia.

Received: December 01, 2025; Published: January 16, 2026

Abstract

The paper presents an experimental method for quantifying the transdermal permeability of cosmetic compositions by incorporating a fluorescent probe – acridone-acetic acid at a concentration of 100 μg/mL – followed by analysis of the extracted acridone-acetic acid in skin samples using HPLC with fluorescence detection. The proposed method was used to investigate the transdermal permeability of individual cosmetic compositions prepared by a standard method and using transdermal permeability enhancement technologies based on the formation of supramolecular complexes.

 Keywords: Transdermal Permeability; Acridone Acetic Acid

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Citation

Citation: AV Troitsky., et al. “Comparative Assessment of Transdermal Permeability of Cosmetic Products”.Acta Scientific Medical Sciences 10.2 (2026): 17-22.

Copyright

Copyright: © 2026 AV Troitsky., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.