Ziad Nasser Almutawa¹*, Nawaf Mansour Almutairi², Saleh Mohammed Alegayel³, Saeed Jalal Albaqami⁴, Anas Ibrahim Alhuzaimi², Ibrahim Mesfer Alqahtani⁵, Khaled Hashim Alolimi⁶, Faisal Ghaithan Alamri⁶, Zainab Saad Alotaibi⁷ and Samaher Mohammed Alhomaidhi⁸

¹Restorative Dentist, Medical Services in Ministry of Interior, Saudi Arabia
²Periodontist, Medical Services in Ministry of Interior, Saudi Arabia
³General Dentist, Medical Services in Ministry of Interior, Saudi Arabia
⁴Endodontist, Alkharj Military Industries Corporation Hospital, Saudi Arabia
⁵Endodontist, Medical Services in Ministry of Interior, Saudi Arabia
⁶Radiology Specialists, Ministry of Interior, Public Security, Medical Services, Riyadh, Saudi Arabia
⁷Pharmacist, King Khalid University Hospital, Saudi Arabia
⁸Dentist, Security Forces Albaha, Saudi Arabia

*Corresponding Author: Ziad Nasser Almutawa, Restorative Dentist, Medical Services in Ministry of Interior, Saudi Arabia.

Received: November 23, 20; Published: December 08, 2025

Abstract

Background: Medication related osteonecrosis of the jaw (MRONJ) is a serious complication of antiresorptive and antiangiogenic therapy. Effective prevention and management depend on coordinated care between dentists, radiologists and pharmacists, we aimed to review the roles of dentists, radiologists and pharmacists in the prevention, diagnosis and management of MRONJ, and summarize their knowledge, clinical practices and interdisciplinary collaboration.

Methods: A systematic search of electronic databases identified original studies reporting MRONJ related knowledge, attitudes, clinical practice, risk factors or outcomes in dentists, radiologists, pharmacists or mixed professional groups. Eligible designs included cross sectional surveys, qualitative studies and observational cohorts. Data were extracted on study characteristics, professional groups, MRONJ focus and main findings, and synthesised in line with PRISMA guidance.

Results: Eleven studies were included: eight cross sectional surveys of dental professionals or pharmacists, one qualitative interview study of general dental practitioners and two retrospective patient cohorts from Europe, the Middle East and Asia. Dental surveys showed high awareness of MRONJ and a gaps in recognising risk factors, clinical features and guideline-based management, as well as inconsistent documentation of antiresorptive therapy and communication with physicians. Cohort data indicated that absence of comprehensive dental care before antiresorptive or antiangiogenic therapy increased MRONJ risk and systemic factors such as chemotherapy, smoking and immunosuppression amplified risk.

Conclusions: included studies support pre treatment dental clearance, systematic medical and medication history taking, and structured pharmacist dentist collaboration, and future research should integrate radiologists into coordinated MRONJ care pathways.

 Keywords: Medication Related Osteonecrosis of the Jaw; Bisphosphonates; Dentists; Radiologists; Pharmacists; Interdisciplinary Care

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Citation

Citation: Ziad Nasser Almutawa., et al. “Prevention, Diagnosis and Management of Medication Related Osteonecrosis of the Jaw: Interdisciplinary Systematic Review of Dentists, Radiologists and Pharmacists Contributions”.Acta Scientific Medical Sciences 10.1 (2026): 12-18.

Copyright

Copyright: © 2026 Ziad Nasser Almutawa., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.