Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Conceptual Paper Volume 9 Issue 11

Nobel Laureate David Baltimore a Revolutionary Molecular Biologist is No More: To Pay Homage a Brief Coverage of His Scientific Contribution with Precision

Tapas Kumar Goswami*

Department of Veterinary Microbiology, Institute of Veterinary Science and Animal Husbandry, Siksha “O” Anusandhan (Deemed to be University), Bhubaneswar-751030, Odisha

*Corresponding Author: Tapas Kumar Goswami, Department of Veterinary Microbiology, Institute of Veterinary Science and Animal Husbandry, Siksha “O” Anusandhan (Deemed to be University), Bhubaneswar-751030, Odisha.

Received: September 22, 2025; Published: October 31, 2025

Abstract

Nobel laureate David Baltimore an eminent virologist turned molecular biologist celebrated for his discovery of the enzyme reverse transcriptase, passed away on 6th September 2025. To pay tribute a deliberate attempt to explain his contribution in science.

 Keywords: Central Dogma of Life; David Baltimore; Nobel Prize; Retrovirus; Reverse Transcriptase; Vesicular Stomatitis Virus

References

  1. Crick FH. “On protein synthesis”. Symposia of the Society of Experimental Biology 12 (1958): 138-163.
  2. Baltimore D “Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of RNA Tumour Viruses”. Nature 226 (1970) 1209-1211.
  3. Coffin J M. “50th anniversary of the discovery of reverse transcriptase”. Molecular Biology of the Cell2 (2021): 91-97.
  4. Baltimore D. “Expression of animal virus genomes”. Bacteriological Review3 (1971): 235-241.
  5. Datta RK and Datta B. “Nobel Prize winners in medicine”. Journal of Indian Medical Association9 (1975): 268-271.
  6. Rous P. “A transmissible avian neoplasm (sarcoma of the common fowl)”. Journal of Experimental Medicine 12 (1910): 696-705.
  7. Gross L. “Spontaneous leukaemia developing in C3H mice following inoculation in infancy, with AK-leukemic extracts, or AK-embrvos”. Proceeding of Society of Experimental Biology Medicine1 (1951): 27-32.
  8. Goswami T K “Tribute to Anthony Epstein who discovered the first human cancer-causing Epstein-Barr virus: The subject in precise on his demise”. Indian Journal of Animal Health1 (2024): 157-161.
  9. Weiss RA and Vogt PK. “100 years of Rous sarcoma virus”. Journal of Experimental Medicine12 (2011): 2351-2355.
  10. Moelling K. “Half a century of the reverse transcriptase-happy birthday!”. Genome Biology1 (2021): 31.
  11. Baltimore D. “Sixty Years of Discovery”. Annual Review of Immunology 37 (2019): 1-17.
  12. Stahl FW. “George Streisinger-December 27,1927-September 5, 1984”. Biographical Memoirs of the National Academy of Sciences 68 (1995): 353-361.
  13. Culliton BJ. “Review of the book Ahead of the Curve: David Baltimore's Life in Science”. Bulletin of the History of Medicine2 (2003): 474-475.
  14. Huang A and Baltimore D. “Defective Viral Particles and Viral Disease Processes”. Nature 226 (1970): 325-327.
  15. Dulbecco R. “Transformation of cells in vitro by DNA-containing viruses”. Journal of American Medical Association 190 (1964): 721-726.
  16. , et al. “Ribonucleic acid synthesis of vesicular stomatitis virus. I. Species of ribonucleic acid found in Chinese hamster ovary cells infected with plaque-forming and defective particles”. Journal of Virology 4 (1969): 154-161.
  17. , et al. “Ribonucleic acid synthesis of vesicular stomatitis virus. II. An RNA polymerase in the virion”. Proceeding of Natural Academy of Sciences 66 (1970): 572-576.
  18. Sitaraman S. “David Baltimore, Renowned Molecular Biologist and Nobel Laureate, Dies at 87”. The Scientist (2025).
  19. , et al. “Stable expression of immunoglobulin gene V (D)J recombinase activity by gene transfer into 3T3 fibroblasts”. Cell 53 (1988): 107-115.
  20. , et al. “The V (D)J recombination activating gene, RAG-1”. Cell 59 (1989): 1035-1048.
  21. Cohen J. “Remembering David Baltimore, a titan who transformed biology and spoke bluntly”. Science 9th (2025).
  22. Baltimore D. “Biographical. Nobel Prize.org. Nobel Prize Outreach”. 14 September (2025).
  23. Weaver D., et al. “Altered repertoire of endogenous immunoglobulin gene expression in transgenic mice containing a rearranged mu heavy chain gene”. Cell2 (1986): 247-259.
  24. Lock S. “The Baltimore case: A trial of politics, science, and character”. British Medical Journal7214 (1999): 926.
  25. Baltimore D. “An interview with David Baltimore by Errol C. Friedberg”. Nature Review Molecular Cell Biology 9 (2008): 670-671.

Citation

Citation: Tapas Kumar Goswami. “Nobel Laureate David Baltimore a Revolutionary Molecular Biologist is No More: To Pay Homage a Brief Coverage of His Scientific Contribution with Precision”.Acta Scientific Medical Sciences 9.11 (2025): 74-78.

Copyright

Copyright: © 2025 Tapas Kumar Goswami. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.403

Indexed In





Contact US