Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Editorial Volume 9 Issue 11

Deep-rooted and Inherent-Intracholecystic Papillary Neoplasm

Anubha Bajaj*

Department of Histopathology, Panjab University/A.B. Diagnostics, India

*Corresponding Author: Anubha Bajaj, Department of Histopathology, Panjab University/A.B. Diagnostics, India.

Received: August 05, 2025; Published: October 01, 2025

Abstract

Intracholecystic papillary neoplasm emerges as a macroscopically discernible, non invasive epithelial neoplasm configuring as mass confined to gallbladder mucosa or a tumour projection into lumen of gallbladder. Initially scripted by Adsay et al in 2012, the neoplasm is contemplated as a distinct subtype of pre invasive neoplasm of gallbladder, as per the contemporary World Health Organization (WHO) classification 2019 [1].

References

  1. Adsay V., et al. “Intracholecystic papillary-tubular neoplasms (ICPN) of the gallbladder (neoplastic polyps, adenomas, and papillary neoplasms that are ≥1.0 cm): clinicopathologic and immunohistochemical analysis of 123 cases”. The American Journal of Surgical Pathology9 (2012): 1279-301.
  2. Watanabe Y., et al. “Intracholecystic papillary neoplasm associated with invasive carcinoma of the remnant gallbladder after subtotal cholecystectomy: a case report”. Surgical Case Reports 1 (2022): 31.
  3. Nakanuma Y., et al. “Pathological characterization of intracholecystic papillary neoplasm: A recently proposed preinvasive neoplasm of gallbladder”. Annals of Diagnostic Pathology 52 (2021): 151723.
  4. Nakanuma Y., et al. “Characterization of high-grade biliary intraepithelial neoplasm of the gallbladder in comparison with intracholecystic papillary neoplasm”. Human Pathology 116 (2021): 22-30.
  5. Yokoda M., et al. “Intracholecystic papillary neoplasm of the gallbladder protruding into the common bile duct: a case report”. Molecular and Clinical Oncology 11 (2019): 488-492.
  6. Mizobuchi N., et al. “Three cases of intracystic papillary neoplasm of gallbladder”. Abdominal Radiology (NY) 43 (2018): 1535-1539.
  7. Pehlivanoglu B., et al. “Intracholecystic tubular non-mucinous neoplasm (ICTN) of the gallbladder: a clinicopathologically distinct, invasion-resistant entity”. Virchows Archives 478 (2021): 435-447.
  8. Taskin OC., et al. “Gallbladder polyps: correlation of size and clinicopathologic characteristics based on updated definitions”. PLoS One9 (2020): e0237979.
  9. Akita M., et al. “Intracholecystic papillary neoplasms are distinct from papillary gallbladder cancers: a clinicopathologic and exome-sequencing study”. The American Journal of Surgical Pathology 43 (2019): 783-791.
  10. Mochidome N., et al. “Prognostic implications of the coexisting precursor lesion types in invasive gallbladder cancer”. Human Pathology 114 (2021): 44-53.
  11. Image 1 Courtesy: Pathology outlines.
  12. Image 2 Courtesy: Journal of current surgery.

Citation

Citation: Anubha Bajaj. “Deep-rooted and Inherent-Intracholecystic Papillary Neoplasm”.Acta Scientific Medical Sciences 9.11 (2025): 01-04.

Copyright

Copyright: © 2025 Anubha Bajaj. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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