Parameshwar Jakinala*, Harikrishna Naik Lavudi, Ushasree Ravula and Madhumohan Rao Katika

Department of Microbiology, StemRegenex Bio Pvt Ltd., Commercial Complex, Asian Suncity, 409, 4th Floor, B Block, Kondapur, Hyderabad, Telangana 500084, India

*Corresponding Author: Madhumohan Rao Katika, Research Scientist and In-charge, StemRegenex Bio Pvt Ltd., Commercial Complex, Asian Suncity, 409, 4th Floor, B Block, Kondapur, Hyderabad, Telangana 500084, India.

Received: July 10, 2025; Published: August 30, 2025

Abstract

Herpes zoster (HZ), caused by the reactivation of latent varicella-zoster virus (VZV) in sensory ganglia, manifests as a painful, unilateral vesicular rash along dermatomal distributions [1]. While antiviral therapies and analgesics mitigate acute symptoms, postherpetic complications such as scarring remain a significant burden. Approximately 10–20% of HZ patients develop hypertrophic or atrophic scars, characterized by dyspigmentation, fibrosis, and impaired skin integrity, which persist despite conventional interventions [2]. These scars contribute to long-term physical discomfort, psychosocial distress, and reduced quality of life, underscoring the need for innovative therapeutic strategies [1].

 Keywords: Herpes Zoster (HZ); Mesenchymal Stem Cells (MSCs); Extracellular Vesicles (EVs)

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Citation

Citation: Parameshwar Jakinala., et al. “Regression of Hypertrophic Scars in Herpes Zoster Using Umbilical Cord Mesenchymal Stem Cells and Plant-Derived Exosomes: A Case Report”.Acta Scientific Medical Sciences 9.9 (2025): 92-95.

Copyright

Copyright: © 2025 Parameshwar Jakinala., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.