Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Research Article Volume 9 Issue 6

Prevalence of H. pylori in Type 2 Diabetes Patients Attending the Nkwen District Hospital, Bamenda – Cameroon

Asanghanwa Milca*, Kehbila Desire Gwelablab and Mary Chia Garba

Department of Medical Laboratory Sciences, Faculty of Health Sciences, University of Bamenda, P. O. Box 39, Bambili, Cameroon

*Corresponding Author: Asanghanwa Milca, Department of Medical Laboratory Sciences, Faculty of Health Sciences, University of Bamenda, P. O. Box 39, Bambili, Cameroon.

Received: March 21, 2025; Published: May 20, 2025

Abstract

Background: Helicobacter pylori is a bacterium suspected to be associated with extra-digestive diseases including diabetes. However, there is limited evidence on the burden and determinants of this bacterial infection within the North West Region of Cameroon. We aimed at investigating the prevalence and risk factors of H. pylori in type 2 diabetes patients attending the Diabetes Clinic of the Nkwen District Hospital, Bamenda – Cameroon.

Methodology: This was a hospital-based case-control and cross-sectional study involving 70 type 2 diabetes patients and 100 non-diabetic controls. Following informed consent, serological testing for H. pylori antibody was performed using H. pylori antibody rapid test kit. H. pylori data regarding prevalence and risk factors were analyzed using Statistical Package for Social Science (SPSS) version 22.0; with p-value < 0.05 considered statistically significant.

Results: The overall prevalence of H. pylori was 64%; with a non-significant disparity according to diabetes: 70% (49/70) in diabetic patients versus 60% (60/100) in non-diabetic controls (p = 0.181). Interestingly, diabetic patients who ate only at home had a significantly lower prevalence of H. pylori (62.9%) compared to those who ate both at home and restaurants (93.8%) (p = 0.018). All other potential factors tested in both groups were not statistically associated with the risk of having H. pylori (p > 0.05).

Conclusion: The prevalence of H. pylori in the general population of the Health District of Nkwen is high regardless of diabetic status. However, type 2 diabetes patients frequenting restaurants stand at a higher risk of carrying H. pylori; suggesting the need for adherence to infection prevention and control measures within community restaurants.

 Keywords: Prevalence; H. pylori; Risk Factors; Bamenda

References

  1. Li J and Perez GI. “Helicobacter pylori the Latent Human Pathogen or and Ancestral Commensal Organism”. Frontiers in Microbiology 9 (2018): 609.
  2. Jay V Solnick and JaniL O’rourke. Peter Vandamme and Adrian Lee (2016).
  3. Merve Öztekin., et al. Diseases (2021): 966.
  4. Feng-Woei Tsay and Ping-I. “Hsuextra-gastroduodenal diseases”. Journal of Biomedical Science 25 (2018).
  5. Seyed Abolfazl Hosseininasab Nodoushan and Amin Nabavi. “The Interaction of Helicobacter pylori Infection and Type 2 Diabetes Mellitus”. Advanced Biomedical Research 8 (2019): 15.
  6. Ramy K Aziz., et al. “Contaminated water as a source of Helicobacter pylori infection: A review”. Journal of Advanced Research 4 (2015): 539-547.
  7. Thai Hoang Che Tu Cam Nguyen., et al. “Factors Associated With Helicobacter Pylori Infection Among School-Aged Children From a High Prevalence Area in Vietnam”. International Journal of Public Health (2023).
  8. Odete Amaral., et al. “Living Conditions and Helicobacter pylori in Adults”. Biomed Research International (2017): 9082716.
  9. Oya Yucel. World Journal of Gastroenterology30 (2014): 10348-10354.
  10. Laure Brigitte Kouitcheu Mabeku., et al. “Helicobacter pylori infection, a risk factor for Type 2 diabetes mellitus: a hospital-based cross-sectional study among dyspeptic patients in Douala-Cameroon”. Scientific Report (2020).
  11. Abdullah M Alzahrani., et al. “Association between type 2 diabetes mellitus and Helicobacter pylori infection among Saudi patients attending National Guard Primary Health Care Centers in the Western Region, 2018”. (2020).
  12. Ebule IA., et al. “Association of Helicobacter Pylori Infection and Diabetes Mellitus Type 2 Subjects in Yaounde Cameroon Using a Panel of Serum Biomarkers (PGII, HpIgG): A Case Control Study”. Journal of Clinical Gastroenterology and Treatment 3 (2017): 053.
  13. Smith S., et al. “Infections with Helicobacter pylori and challenges encountered in Africa”. World Journal of Gastroenterology25 (2019): 3183-3195.

Citation

Citation: Asanghanwa Milca., et al. “Prevalence of H. pylori in Type 2 Diabetes Patients Attending the Nkwen District Hospital, Bamenda – Cameroon”.Acta Scientific Medical Sciences 9.6 (2025): 73-78.

Copyright

Copyright: © 2025 Asanghanwa Milca., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.403

Indexed In





Contact US