Jory Oudah Alanazi¹* and Riham Syed²

¹Princess Nourah Bint Abdulrahman University, King Fahad Medical City, Riyadh, Saudi Arabia
²Lecturer, Department of Health and Rehabilitation Sciences, Princess Nourah Bint Abdulrahman University, King Fahad Medical City, Riyadh, Saudi Arabia

*Corresponding Author: Jory Oudah Alanazi, Princess Nourah Bint Abdulrahman University, King Fahad Medical City, Riyadh, Saudi Arabia.

Received: May 02, 2025; Published: May 09, 2025

Abstract

Introduction: Breast cancer is the most common cancer in Saudi women. There am various types of breast cancer treatment modalities such as, surgery, chemotherapy, radiotherapy, hormone therapy, and biological therapy. Surgery is generally the first step and there am different types of breast cancer surgery that includes Breast Conservative Surgery, and Modified Radical Mastectomy. Recent research shows women with breast cancer and depression am at higher risk of cancer recurrence and early death than breast cancer patients without depression.

Objective: Evaluation of the presence and severity of symptoms of depression in women treated for breast cancer who underwent surgical procedure using one of two methods, either Modified Radical Mastectomy (MRM) or Breast Conserving Surgery (BCS).

Method: A questionnaire survey involved 10 patients treated in a conservative surgery and 10 patients after Modified Radical Mastectomy. Hamilton rating scale for depression was used in the study. The patient's responses was statically analyzed.

Results: Based on Hamilton Rating Scale for Depression (HAMD) questionnaire, the depression level in the group of women treated with MRM was higher than patients who had undergone BCS. The survey conducted showed that 45% of patients after Modified Radical Mastectomy suffered from severe depression as long with the 10% patients who had BCS, while 5% who had MRM suffered from mild depression and 40% from BCS patients had suffered the same as well. T-Test conformed that the noticed differences was statistically significant, p < 0.000232 in BCS and MRM.

Conclusion: Symptoms of depression was more pronounced among women who underwent MRM compared to those who received BCS. While the surgical technique plays a significant role in psychological response, other variables such as cancer stage, type of adjuvant therapy, and personal circumstances may also influence emotional outcomes. Future research should explore these contributing factors in more depth. Psychological support must be integrated into routine breast cancer care, with tailored strategies for high-risk patients.

 Keywords: Breast Cancer; MRM; BCS; Depression

References

1. MOH Team. “Kingdom of saudi arabia - ministry of health portal”. (Moh.gov.sa, 2015).
2. “Cancer Incidence Report Saudi Arabia 2010” (2015).
3. Medical News Today. “Breast Cancer: Causes, Symptoms and Treatments” (2015).
4. org. stages Of Breast Cancer|Breastcancer.org. (2015).
5. googleusercontent.com. William E Kahlert. Regional Cancer Center (2015).
6. org. “Surgery For Breast Cancer”. (2015).
7. “Types Of Breast Cancer Surgery”. (2015).
8. com. “Lumpectomy| Breast Cancer Treatment | Imaginis-The Women’s Health and Wellness Resource Network”. (2015).
9. Types surgery. “Types Of Breast Cancer Surgery | Cancer Research UK' (Cancerresearchuk.org, 2015).
10. com. “Surgical Procedures for Breast Cancer — Mastectomy and Breast Conserving Therapy”. (2015).
11. José Manuel García Arroyo and María Luisa Domínguez López. “Psychological problems derived from mastectomy: a qualitative study”. International Journal of Surgical Oncology (2011).
12. Ammapattian Thirumoorthy and others. “Quality of life in cancer patients with disfigurement due to cancer and its treatments”. Indian Journal of Palliative Care (2011).
13. Net. “Depression” (2013).
14. News Center. “Depression's effect on immune system may worsen cancer, study suggests” (2007).
15. Yasmin Farooqi. “Depression and anxiety in mastectomy cases”. (2015).
16. Lim CC., et al. “Anxiety in women with breast cancer undergoing treatment: a systematic review”. International Journal of Evidence-Based Healthcare 3 (2011): 215-235.
17. com. “Breast Cancer - In-Depth Report - NY Times Health”. (2015).
18. Kamińska M., et al. “Evaluation of symptoms of anxiety and depression in women with breast cancer after breast amputation or conservation treated with adjuvant Chemotherapy”. Annals of Agricultural and Environmental Medicine 1 (2015): 185-189.
19. Sun Y., et al. “Comparison of quality of life based on surgical technique in patients with breast Cancer”. Japanese Journal of Clinical Oncology 1 (2014): 22-27.

Citation

Citation: Jory Oudah Alanazi and Riham Syed. “Evaluation of Symptoms of Depression in Women with Breast Cancer after Modified Radical Mastectomy and Breast Conservative Surgery”.Acta Scientific Medical Sciences 9.6 (2025): 37-42.

Copyright

Copyright: © 2025 Jory Oudah Alanazi and Riham Syed. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.