Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Editorial Volume 9 Issue 6

Sedation Strategies in Bronchoscopy: The Effectiveness of Benzodiazepines in Clinical Practice

Marco Umberto Scaramozzino1*, Francesco Luppino2, Orazio Pardeo2, Veronica Nassisi3, Angelo Coppola4,5, Giovanni Sapone6 and Domenico Caratozzolo7

1Head of Thoracic Endoscopy and Rehabilitation Pulmonology Services, Villa Aurora Hospital Reggio Calabria, Italy
2U.O.C. Neurology and Neuromuscular Disorders, Department of Clinical and Experimental Medicine, University of Messina, Italy
3General Medicine Unit, San Camillo Nursing Home, Messina, Italy
4UOC Pneumologia, Ospedale San Filippo Neri-ASL Roma 1, 00135 Rome, Italy
5UniCamillus, Saint Camillus International University of Health Sciences, 00131 Rome, Italy
6Head Nurse, Cardiology Department, Madonna della Consolazione Polyclinic, Reggio Calabria, Italy
7U.O.C. Pulmonology – University Policlinic “Gaspare Rodolico” of Catania, University of Catania, Italy

*Corresponding Author: Marco Umberto Scaramozzino, Head of Thoracic Endoscopy and Rehabilitation Pulmonology Services, Villa Aurora Hospital Reggio Calabria, Italy.

Received: April 02, 2025; Published: May 01, 2025

Abstract

Sedation during bronchoscopy is crucial to ensure patient comfort and procedural success. Benzodiazepines, such as midazolam, are commonly used to achieve sedation and anterograde amnesia, reducing anxiety and improving the patient’s experience. These drugs, due to their anxiolytic, amnesic, and sedative effects, are frequently employed for moderate sedation during diagnostic procedures. However, the safety profile and effectiveness of benzodiazepines, particularly in comparison with other sedatives like remimazolam, have been the subject of numerous studies.

Recent studies suggest that remimazolam, a newer generation benzodiazepine, offers significant advantages over midazolam, such as faster onset, more controlled duration of action, and better neurological recovery with a lower risk of side effects like respiratory depression. Furthermore, in elderly or high-risk patients, remimazolam appears to be a preferable choice to ensure deep sedation with safer management of the airway.

Despite these advancements, the use of benzodiazepines in bronchoscopy sedation still requires careful assessment of individual patient characteristics and specific clinical needs, to optimize benefits and minimize risks.

 Keywords: Sedation; Bronchoscopy

References

  1. José RJ., et al. “Sedation for flexible bronchoscopy: current and emerging evidence”. European Respiratory Journal 128 (2013): 106-116.
  2. Zhou Y., et al. “Efficacy and safety of remimazolam in bronchoscopic sedation: A meta-analysis”. World Journal of Clinical Cases6 (2024): 1120-1129.
  3. Kim SH., et al. “Safety and efficacy of remimazolam compared with midazolam during bronchoscopy: a single-center, randomized controlled study”. Scientific Report 13 (2023): 20498.
  4. Wu Qiuyue MM., et al. “Bolus administration of remimazolam was superior to midazolam for deep sedation in elderly patients undergoing diagnostic bronchoscopy: A randomized, double-blind, controlled trial”. Medicine12 (2024): e37215.
  5. Noor N., et al. “A comprehensive review of remimazolam for sedation”. Health Psychology Research1 (2021).
  6. "Digestive Endoscopy and Sedation".
  7. "Sedation and Analgesia for Endoscopic Examination".
  8. "Digestive Endoscopy and Sedation”.
  9. "Gastroscopy with or without Sedation".
  10. "Neuroleptoanalgesia".

Citation

Citation: Marco Umberto Scaramozzino., et al. “Sedation Strategies in Bronchoscopy: The Effectiveness of Benzodiazepines in Clinical Practice”.Acta Scientific Medical Sciences 9.4 (2025): 01-03.

Copyright

Copyright: © 2025 Marco Umberto Scaramozzino., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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