Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Research Article Volume 9 Issue 2

Safety and Efficacy of Continuous Positive Airway Pressure in Pediatric Younger than One Year with Acute Bronchiolitis; Systematic Review

Nawaf Khalid Al Hammadi*, Ali Jamah Alghamdi, Mobarak Moufi Aldossari, Abdullealah Saad Alshahrani, Waleed Mohammed Abu Alghayth, Abdulrhman Rasheed Almutairi, Jomana Salem Almogbel, Modhy Khalid Albuqami, Renad Turki Alotaibi, Hanan Abdulrahman Alshahrani and Haitham Abdullah Alzahrani

Respiratory Therapist, Respiratory Care Services, Pediatric Department, Prince Sultan Military Medical City, Riyadh, Saudi Arabia

*Corresponding Author: Nawaf Khalid Al Hammadi, Respiratory Therapist, Respiratory Care Services, Pediatric Department, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.

Received: December 06, 2024; Published: January 20, 2025

Abstract

We aimed to look into efficiency of CPAP delivery techniques and see whether using CPAP may be therapeutically helpful for pediatric with bronchiolitis. This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement (PRISMA). We searched PubMed, EMBASE, and the Cochrane Library between 2015 and 2024. The main search phrases were CPAP and bronchiolitis. We considered RCTs, with children under 12 months of age complain of bronchiolitis, and contrasted CPAP with other respiratory support techniques or CPAP enhanced in different ways. For young children with bronchiolitis, HFNC may be a helpful alternative to CPAP. CPAP use did not reduce the need for mechanical ventilation in children with bronchiolitis, despite the weak evidence. Little to no data suggests that children with bronchiolitis who received CPAP fared better. In young infants with moderate to severe bronchiolitis, the failure rate of first HFNC treatment was not comparable to that of nCPAP. When using a helmet instead of a face mask, CPAP is more pleasant and requires less sedation. Both nasal prong-administered and helmet-administered CPAP are equally beneficial for treating acute bronchiolitis in young children.

 Keywords: Continuous Positive Airway Pressure; Acute Bronchiolitis; Efficacy; Safety

References

  1. Nicolai A., et al. “Viral bronchiolitis in children: A common condition with few therapeutic options”. Early Human Development 89 (2013): S7-11.
  2. Sanz JP. “Bronchitis and bronchiolitis”. Pediatria Integral 20 (2016): 28-
  3. Zorc JJ and Hall CB. “Bronchiolitis: Recent Evidence on Diagnosis and Management”. Pediatrics 2 (2010): 342-349.
  4. Nair H., et al. “Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis”. Lancet 9725 (2010): 1545-1555.
  5. Stockman LJ., et al. “Respiratory Syncytial Virus-associated Hospitalizations Among Infants and Young Children in the United States, 1997-2006”. The Pediatric Infectious Disease Journal1 (2012): 5-9.
  6. Zhang Q., et al. “Respiratory syncytial virus - associated intensive care unit admission in children in Southern China”. BMC Research Notes1 (2013): 447.
  7. Feltes TF., et al. “Palivizumab prophylaxis reduces hospitalization due to respiratory syncytial virus in young children with hemodynamically significant congenital heart disease”. Journal of Pediatrics4 (2003): 532-540.
  8. Fujiogi M., et al. “Trends in Bronchiolitis Hospitalizations in the United States: 2000-2016”. Pediatrics 6 (2019): e20192614.
  9. Alharbi A., et al. “Bronchiolitis in children: The Saudi initiative of bronchiolitis diagnosis, management, and prevention (SIBRO)”. Annals of Thoracic Medicine3 (2018): 127.
  10. Rsovac S., et al. “Complications of Mechanical Ventilation in Pediatric Patients in Serbia”. Advances in Clinical and Experimental Medicine 1 (2014): 57-61.
  11. Yaman A., et al. “Efficacy of noninvasive mechanical ventilation in prevention of intubation and reintubation in the pediatric intensive care unit”. Journal of Critical Care 32 (2016): 175-181.
  12. Cambonie G., et al. “Nasal continuous positive airway pressure decreases respiratory muscles overload in young infants with severe acute viral bronchiolitis”. Intensive Care Medicine10 (2008): 1865-1872.
  13. Jat KR and Mathew JL. “Continuous positive airway pressure (CPAP) for acute bronchiolitis in children”. Cochrane Database System Review 1 (2019).
  14. Moher D., et al. “Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement”. PLoS Medicine7 (2009): e1000097.
  15. Mayordomo-Colunga J., et al. “Helmet Versus Nasal-Prong CPAP in Infants With Acute Bronchiolitis”. Respiratory Care4 (2018): 455-463.
  16. Chidini G., et al. “Continuous Positive Airway Pressure With Helmet Versus Mask in Infants With Bronchiolitis: An RCT”. Pediatrics 4 (2015): e868-875.
  17. Milési C., et al. “High flow nasal cannula (HFNC) versus nasal continuous positive airway pressure (nCPAP) for the initial respiratory management of acute viral bronchiolitis in young infants: a multicenter randomized controlled trial (TRAMONTANE study)”. Intensive Care Medicine 2 (2017): 209-216.
  18. Vahlkvist S., et al. “High flow nasal cannula and continuous positive airway pressure therapy in treatment of viral bronchiolitis: a randomized clinical trial”. European Journal of Pediatrics3 (2020): 513-518.
  19. Sinha R., et al. “Comparative Study between Noninvasive Continuous Positive Airway Pressure and Hot Humidified High-flow Nasal Cannulae as a Mode of Respiratory Support in Infants with Acute Bronchiolitis in Pediatric Intensive Care Unit of a Tertiary Care Hospital”. Indian Journal of Critical Care Medicine 22.2 (2018): 85-90.
  20. Agüera M., et al. “Safety and effectiveness of bubble continuous positive airway pressure as respiratory support for bronchiolitis in a pediatric ward”. European Journal of Pediatrics12 (2022): 4039-4047.
  21. Borckink I., et al. “Infants with severe respiratory syncytial virus needed less ventilator time with nasal continuous airways pressure then invasive mechanical ventilation”. Acta Paediatrics1 (20144): 81-85.
  22. Lazner MR., et al. “Non‐invasive ventilation for severe bronchiolitis: Analysis and evidence”. Pediatric Pulmonology9 (2012): 909-916.
  23. Essouri S., et al. “Improved clinical and economic outcomes in severe bronchiolitis with pre-emptive nCPAP ventilatory strategy”. Intensive Care Medicine 1 (2014): 84-91.
  24. Service specifications (2018) Paediatric high dependency care. National Health System. England (2018).
  25. Essouri S., et al. “Optimal level of nasal continuous positive airway pressure in severe viral bronchiolitis”. Intensive Care Medicine12 (2011): 2002-2007.
  26. Lin J., et al. “High-flow nasal cannula therapy for children with bronchiolitis: a systematic review and meta-analysis”. Archives of Disease in Childhood6 (2019): 564-576.
  27. Metge P., et al. “Comparison of a high-flow humidified nasal cannula to nasal continuous positive airway pressure in children with acute bronchiolitis: experience in a pediatric intensive care unit”. European Journal of Pediatrics7 (2014): 953-958.
  28. Pedersen M and Vahlkvist S. “Comparison of CPAP and HFNC in Management of Bronchiolitis in Infants and Young Children”. Children4 (2017): 28.
  29. Thia LP., et al. “Randomised controlled trial of nasal continuous positive airways pressure (CPAP) in bronchiolitis”. Archives of Disease in Childhood1 (2008): 45-47.
  30. Cambonie G., et al. “Nasal continuous positive airway pressure decreases respiratory muscles overload in young infants with severe acute viral bronchiolitis”. Intensive Care Medicine 10 (2008): 1865-1872.
  31. Martinon-Torres F., et al. “Nasal continuous positive airway pressure with heliox versus air oxygen in infants with acute bronchiolitis: a crossover study”. Pediatrics5 (2008): e1190-e1195.
  32. Ganu SS., et al. “Increase in use of noninvasive ventilation for infants with severe bronchiolitis is associated with decline in intubation rates over a decade”. Intensive Care Medicine 7 (2012): 1177-1183.
  33. Javouhey E., et al. “Non-invasive ventilation as primary ventilatory support for infants with severe bronchiolitis”. Intensive Care Medicine 9 (2008): 1608-1614.

Citation

Citation: Nawaf Khalid Al Hammadi., et al. “Safety and Efficacy of Continuous Positive Airway Pressure in Pediatric Younger than One Year with Acute Bronchiolitis; Systematic Review”.Acta Scientific Medical Sciences 9.2 (2025): 69-74.

Copyright

Copyright: © 2025 Nawaf Khalid Al Hammadi., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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