Toxicological Effects of Carbendazim: A Review
Muhammad Hashim1*, Atef M Al-Attar1,2 and Isam M Abu Zeid1,2
1Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia
2Princess Dr. Najla Bint Saud Al-Saud Center for Excellence Research in Biotechnology, King Abdulaziz University, Jeddah, Saudi Arabia
*Corresponding Author: Muhammad Hashim, Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.
March 06, 2023; Published: March 31, 2023
Pesticides are usually inorganic substances used in agriculture to control various types of crops to kill insects and pests, weeds, rodents, fungi, and unwanted microorganisms. The biggest challenge today is that they are not limited to the agrochemical sector but are also used in households to kill mosquitoes, eliminate fungal and microbial activities that contaminate kitchens and food. One of these chemicals used as a fungicide to prevent fungal attack is carbendazim (CBZ) or methyl-1H-benzimidazol-2-yl-carbamate (MBC), one of the many chemicals used to protect crops from fungal attack. Several studies have been conducted to investigate the toxicological effects of CBZ on organismal health, environmental contamination, detection, and degradation. These studies have evaluated biochemical and histopathological changes in the liver, kidney, and testes, as well as concerns related to dermal, oral, and respiratory exposure to lethal and sublethal doses of CBZ. The current challenge is to develop less hazardous or organic alternatives to protect the environment and human health. This review highlights the hazards associated with CBZ and discusses potential alternative organic chemotherapeutics that are health friendly to the environment and organismic health.
Keywords: CBZ, health risks, environmental toxicity, degradation, organic chemotherapeutics.
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