F Zerdoumi¹*, M Medjamia¹, S Boudani¹ and K Djoudad¹

¹Department of Nephrology Hemodialysis Renal Transplantation, Faculty of Medicine Oran, University I. Research Project N ° D00L04UN31012019002, Algeria
²Anatomical Pathology Department, Faculty of Medicine Oran, University I. Research Project N ° D00L04UN31012019002, Algeria

*Corresponding Author: F Zerdoumi, Department of Nephrology Hemodialysis Renal Transplantation, Faculty of Medicine Oran, University I. Research Project N ° D00L04UN31012019002, Algeria.

Received: December 29, 2021; Published: March 16, 2022

Abstract

Introduction: Early identification of kidney disease is an essential step in optimizing management. To this end, we present to you the anatomo-clinical description of the main nephropathies of our department during the interval from 01.09.2017 to 28.02.2021.

Material and Methods: 180 renal biopsies were performed during this interval. Our study is prospective and descriptive. It relates to the study of the frequency, and the anatomo-clinical specificity of nephropathies. Any adult patient over 16 years old with kidney disease was included in the study; descriptive analysis was done by Microsoft Excel2010.

Results: Average age 33.94 ± 15.06 years with overall male to female ratio 1.12. Among primary nephropathies, lipoid nephrosis dominates (33.33% including 25% MCD and 8.33% FSGS) followed by MGN (10%), IgA nephropathy (5.55%), DPGN (2.77%), Crescentic GN (2.21%), CIN (2.22%) and AIN (1.6%). For secondary nephropathies, lupus nephropathy dominates (20%) followed by AA amyloidosis (3.33%). Nephrotic syndrome (74%) represents the most frequent reason for renal biopsy. Histologically, with regard to the low chronicity index compared to 00 globally sclerotic glomeruli (75%) and absence of interstitial fibrosis (77%).

Discussion and Conclusion: In comparison with the data from the African Registry of the main glomerular nephropathies (Plos one 2016; 11 (5); e0152203), the Nephrotic syndrome remains the main reason for renal biopsy and the transition observed in Tunisia [1] (little amyloidosis and DPGN) matches our results with however a predominance of lipoid nephrosis.

Keywords: Crescentic; Glomerular Nephropathies; Algeria

References

1. Ben Maiz H., et al. “Epidemiology of glomerular diseases in Tunisia from 1975-2005. Influence of changes in healthcare and society”. Bulletin de l'Académie nationale de médecine2 (2006): 403-416.
2. GBD CKD collaboration. “Global, regional, and national of CKD, 1990-2017 a systematic analysis for the global burden of disease study 2017”. Lancet10225 (2020): 709-733.
3. Katia Berkouche., et al. “ESRKD in Sidi Bel Abbes, Algeria: Epidemiological profile of hemodialysis patients from 2015 to 2018”. Clinical Epidemiology and Global Health V12 (2021) 100808.
4. F Zerdoumi., et al. “Delayed orientation in Nephrology, about the experience of EHU Oran”. 18^th Congress of the Society Algérienne d’HTA 09.10. (2021).
5. Ikechi G Okpechi., et al. “Epidemiology of histologically proven glomerulonephritis in Africa. A systematic review and meta analysis”. Plos One3 (2016): e0152203.
6. Giliane Nanchen., et al. “Incidences of glomerulonephritis in the western part of Switzerland over the last decade”. Swiss Medical Weekly 150 (2020): w20353.
7. Steward JH., et al. “ESRD incidence group study”. Geographic, ethnic, age-related and temporal variation in the incidence of end stage renal disease in Europe, Canada, and Asia Pacific region 1998-2002. NDT 21.8 (2006): 2178-2183.
8. Center for disease control and prevention - Chronic kidney diseases surveillance system website (2021).
9. Sim JJ., et al. “ESRD and mortality outcomes across different glomerulonephropathies in a large diverse US population”. Mayo Clinic Proceedings 2 (2018): 167-178.

Citation

Citation: F Zerdoumi., et al. “Epidemiological Profile of Glomerular Nephropathies in the Oran Region West Algeria”.Acta Scientific Medical Sciences 6.4 (2022): 115-118.

Copyright

Copyright: © 2022 F Zerdoumi., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.