Haytham Dahlwi*, Rana Zaini and Mazen Almehmadi

Clinical Laboratory Sciences, Taif University, Saudi Arabia

*Corresponding Author: Haytham Dahlawi, Associate Professor, Hematology, Clinical Laboratory Department, College of Applied Medical Science, Taif University, Taif, Saudi Arabia.

Received: July 28, 2021; Published: August 13, 2021

Abstract

Introduction: On March 2020, the World Health Organization (WHO) introduced the disease of Coronavirus 2019 (COVID-19) as a pandemic disorder. Although Covid-19 has spread rapidly causing serious health problems and might lead to death no effective treatment has discovered yet, the detection of reliable and useful prognostic markers is helpful to predict the severity and prognosis among Covid-19 patients. Thus, the current study aimed to assess and compare the level of WBCs, lymphocytes, neutrophils, monocytes and platelets in Covid-19 patients and control group. This study also evaluated neutrophils to lymphocytes, monocytes to lymphocytes and platelets to lymphocytes ratio.

Methods: This is a retrospective study included 385 participants 350 of which were confirmed COVID- 19 cases. Whereas the control group include 35 healthy individuals.

Results: The result of this study showed a significant increase in total WBCs count, significant low lymphocytes count and significant high neutrophil count in Covid-19 patients admitted in intensive care unit (ICU) compared to the control group. The result of this study also reported significantly (P < 0.0001) higher values for neutrophil-to-lymphocyte ratio (NLR), monocytes-to-lymphocyte ratios (MLR) and platelet-to-lymphocyte ratio (PLR), in Covid-19 patients admitted in ICU.

Conclusion: Based on the findings of this study, which revealed significant changes in a number of blood cells among Covid-19 patients admitted to ICU, it is suggested that level of WBCs, NLR, MLR and PLR can be use as a useful prediction marker to predict the severity of Covid-19 cases in ICU.

Keywords: White Blood Cells; Neutrophils to Lymphocytes Ratio; Monocytes to Lymphocytes Ratio and Platelets to Lymphocytes Ratio; Covid-19

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Citation

Citation: Haytham Dahlwi., et al. “WBCs, Neutrophils to Lymphocytes, Monocytes to Lymphocytes and Platelets to Lymphocytes Ratios to Predict the Severity of Covid-19 Cases among Intensive Care Unit Patients”.Acta Scientific Medical Sciences 5.9 (2021): 57-62.

Copyright

Copyright: © 2021 Haytham Dahlwi., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.