Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Research Article Volume 4 Issue 9

Prediction of Fall among Patients with Parkinson’s Disease: A Cross-Sectional Study, India

Aiswarya Anilkumar1*, M Bagwandsas2 and Geetha Veliah3

1Senior Research Associate, Indian Institute of Public Health, Hyderabad, India
2Professor, Head and Professor of Statistics, SRM Institute of Science and Technology, Chennai, India
3Assistant Professor, MSc Health Education and Community Health Promotion, SRM School of Public Health, SRM Institute of Science and Technology, Chennai, India

*Corresponding Author: Aiswarya Anilkumar, Senior Research Associate, Indian Institute of Public Health, Hyderabad, India.

Received: July 23, 2020; Published: August 18, 2020

×

Abstract

Background: The cross-sectional study aimed to identify the risk factors that lead to fall among patients with Parkinson’s disease, assess the stage of severity; its contribution to fall, and also predict fall among the patients.

Methods: 94 patients diagnosed with Parkinson’s disease were included using non-probability convenience sampling. A semi-structured questionnaire was employed to understand the demographic data, risk factors, disease severity, balance, and level of functioning using the Hoehn and Yahr scale, Berg Balance scale and Activities-Specific Balance Confidence scale respectively. Regression analysis was performed to identify the risk factors that lead to fall. A logistic regression analysis was performed to predict fall and Multivariate Analysis of Variance was employed to understand the difference in scores concerning the different stages of severity.

Results: The regression model showed that the Activities-Specific Balance Confidence score and severity of disease are the strongest contributing risk factors of fall among the participants (p < 0.001). Using Multivariate Analysis of Variance we conclude that there is a significant difference in the average mean Activities-Specific Balance Confidence score from 52.45 to 28.57 when patient proceeds to stage 3 (mild to moderate bilateral disease) from stage 2.5 (mild bilateral disease with recovery on pull test) according to the Hoehn and Yahr staging. Activities- Specific Balance Confidence score which in turn implies the level of functioning was found to be the variable used for prediction of fall.

Conclusion: An effective awareness regarding the stage transition where there is a high risk of fall needs to be understood. The Activities-Specific Balance Confidence score helps us predict the risk of fall among patients.

Keywords: Parkinson's disease (India); Fall Prediction; ABC Scale; Berg Balance Score; Hoehn and Yahr Scale; MANOVA; Disease Severity; Regression

×

References

  1. Custodio N., et al. “Predictive model for falling in Parkinson disease patients”. eNeurologicalSci 5 (2016): 20-24.
  2. Mhyre TR., et al. “Protein Aggregation and Fibrillogenesis in Cerebral and Systemic Amyloid Disease”. 65 (2012): 389-455.
  3. Surathi P., et al. “Research in Parkinson’s disease in India: A review”. Annals of Indian Academy of Neurology 1 (2016): 9-20.
  4. Bala A and Gupta B. “Parkinson′s disease in India: An analysis of publications output during 2002-2011”. International Journal of Nutrition, Pharmacology, Neurological Diseases3 (2013): 254.
  5. Homann B., et al. “The impact of neurological disorders on the risk for falls in the community dwelling elderly: A case-controlled study”. BMJ Open11 (2013): 1-9.
  6. Contreras A and Grandas F. “Risk of falls in Parkinson’s disease: A cross-sectional study of 160 patients”. Parkinson’s Disease (2012).
  7. Zecevic AA., et al. “Defining a fall and reasons for falling: Comparisons among the views of seniors, health care providers, and the research literature”. Gerontologist3 (2006): 367-376.
  8. Lindholm B., et al. “Prediction of falls and/or near falls in people with mild Parkinson’s disease”. PLoS One1 (2015): 1-11.
  9. Allen NE., et al. “Recurrent falls in Parkinson’s disease: A systematic review”. Parkinson’s Disease (2013).
  10. Division of Health Promotion and Disease Prevention Institute of Medicine. Falls in Older Persons: Risk Factors and Prevention. The Second Fifty Years: Promoting Health and Preventing Disability (1992): 263-290.
  11. Stack EL and Roberts HC. “Slow down and concentrate: Time for a paradigm shift in fall prevention among people with Parkinson’s disease?”. Parkinson’s Disease (2013).
  12. Ray Dorsey E., et al. “Global, regional, and national burden of Parkinson’s disease, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016”. Lancet Neurology11 (2018): 939-953.
  13. Bhidayasiri R and Tarsy D. “Movement Disorders: A Video Atlas”. Movement Disorders: A Video Atlas (2012): 4-6.
  14. Krzyszton K., et al. “Evaluation of balance disorders in Parkinson’s disease using simple diagnostic tests - Not so simple to choose”. Frontiers in Neurology 9 (2018): 1-7.
  15. Instructions G. “Berg Balance Tests and Rating Scale” 2-5.
  16. Moore DS., et al. “The Activities-specific Balance Confidence (ABC) Scale * The Activities-specific Balance Confidence (ABC) Scale”. Research Quarterly for Exercise and Sport 1 (2011): 545-554.
  17. Butz AM. “Myocardial Extraction from Newborn Rats”. Physiology Behavior12 (2017): 139-148.
  18. Engdahl S. “Neurodegenerative Disorders” (2013).
  19. Liu FC., et al. “Familial aggregation of Parkinson’s disease and coaggregation with neuropsychiatric diseases: A population-based cohort study”. Clinical Epidemiology 10 (2018): 631-641.
  20. Mak MKY and Pang MYC. “Balance confidence and functional mobility are independently associated with falls in people with Parkinson’s disease”. Journal of Neurology 256 (2009): 742-749.
×

Citation

Citation: Aiswarya Anilkumar., et al. “Prediction of Fall among Patients with Parkinson’s Disease: A Cross-Sectional Study, India". Acta Scientific Medical Sciences 4.9 (2020): 18-25.




Metrics

Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.403

Indexed In





News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is April 30th, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US