Acta Scientific Gastrointestinal Disorders (ASGIS)(ISSN: 2582-1091)

Case Report Volume 4 Issue 6

Asymptomatic Primary Biliary Cirrhosis Revealed by Non Convulsive Status Epilepticus

Oumerzouk Jawad1*, Louhab Nissrine2, Chraa Mohamed2 and Kissani Najib2

1Neurology Department, Military Hospital of Marrakech, Avicenne, Morocco
2Neurology Department, Mohamed VI Hospital, Marrakech, Morocco

*Corresponding Author: Oumerzouk Jawad, Neurology Department, Military Hospital of Marrakech, Avicenne, Morocco.

Received: May 03, 2021; Published: May 11, 2021


  We report the case report of a 71-year-old patient admitted for confusional syndrome. The electroencephalogram showed electrical signs in favor of a status epilepticus with a slowing of the background activity and recording of numerous epileptic spike-wave discharges, quasi-continuous and rhythmic. The ionogram showed hepatic cholestasis with hepatocellular insufficiency: GGT = 71 ui/l (7 - 50), PAL = 196 ui/l (32 - 91), ASAT = 61 ui/l (15 - 41), ALAT = 38 ui/l (14 - 54), total bilirubin = 35 mg /l (3 - 12), direct bilirubin = 8 mg/l (1 - 5), hyperammonemia = 126.2 mol/l (11 - 51) with TP = 66%, TCA = 42/33 and hypoalbuminemia = 23 g/l (35 - 50). The immunological assessment showed the positivity of the antinuclear antibodies (titer> 320) and of the anti-mitochondria antibodies (IFI), with negative anti-LKM1 and anti-smooth muscle antibodies. The patient received symptomatic treatment of hepatic encephalopathy, combined with an antiepileptic treatment based on levetiracetam 500 mg, twice a day, and treatment with azathioprine 50 mg, twice a day, combined with ursodeoxycholic acid. Regular monitoring did not record a relapse. In conclusion, a non-convulsive status epilepticus in an elderly patient with biological cholestasis should suggest the diagnosis of PBC.

Keywords: Epilepticus; Status; Cholestasis


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Citation: Oumerzouk Jawad., et al. “Asymptomatic Primary Biliary Cirrhosis Revealed by Non Convulsive Status Epilepticus”. Acta Scientific Gastrointestinal Disorders 4.6 (2021): 28-31.


Copyright: © 2021 Oumerzouk Jawad., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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