Adhikari Ganga D¹*, Sharma Nitu¹, Gnawali Suman¹, Mandal Sandeep¹, Chaudhary Amardeep², Yadav Ajay Kumar² and Paudel Sangeeta³

¹Department of Radio-Diagnosis, Imaging and Nuclear Medicine, BP Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, Nepal
²Nuclear Medicine and Molecular Imaging Centre, Birat Medical College Teaching Hospital, Tankisinuwari, Budiganga-2, Morang, Nepal
³Department of Dermatology, Chitwan Medical college, Bharatpur, Nepal

*Corresponding Author: Adhikari Ganga D, Department of Radio-Diagnosis, Imaging and Nuclear Medicine, BP Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, Nepal.

Received: August 21, 2025; Published: October 14, 2025

Abstract

Background: Breast cancer is a significant health concern in Nepal, ranking as the second most common cancer among women and the third overall cancer in the country. This study aims to evaluate clinical and demographic characteristics of patients with breast carcinoma on the basis of clinical history and Contrast Enhance Computed Tomography (CECT) report at BP Koirala Memorial Cancer Hospital (BPKMCH), Bharatpur, Nepal.

Methodology: Prospective observational study was performed in Department of Radio diagnosis, Imaging and Nuclear Medicine, BPKMCH. Total 209 diagnosed patients with breast carcinoma underwent to CECT of chest and abdomen and clinical history was obtained simultaneously. The different observational study of CECT chest with abdomen was done with the measurement of mass, lymph node size and different other parameters including distance metastasis. Data was analyzed using IBM SPSS version 20 and Microsoft excel. Pearson’s Correlation was used to see the relation between different parameter and significance level was kept at p < 0.05.

Results: Majority of the breast cancer patients (77.50%) were within the age range of 36-65 years. In all 209 patients, mean size tumor size was 37 x 31 x 30 with standard deviation (SD) ± 20.124. Most of the breast cancer patients 115 out of 209 had painless lump i.e. 55.02%, following 90 patients had painful lump i.e. 43.06%. Among all patients, 82 patients had right breast carcinoma i.e.  39.23%, 125 patients had left breast i.e. 59.80% and 2 patients had bilateral breast carcinoma i.e. 00.95%. Similarly, 147 patients had lymph node metastasis i.e. 70.33%, 56 patients didn’t have lymph node metastasis i.e. 26.80% and only 2 patients had reactive lymph node i.e. negligible. 80 patients were at early stage i.e. 38.27% and 129 patients were at advance stage i.e.  61.73%. Most of the patients 188 didn’t have distance metastasis i.e. 89.5% whereas only 21 patients had distance metastasis status i.e. 10.05%.

Conclusion: In our study breast carcinoma was more common within the age range of 35-56 years age. Majority of the breast cancer patients detected at early stage who can be treated as radical treatment. Regular screening of this age group will help to early detection of breast carcinoma.

keywords: Breast Carcinoma; Contrast Enhance Computed Tomography; Distance Metastasis; Lymph Node; Malignant Mass

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Citation

Citation: Adhikari Ganga D.,et al. “Clinical and Demographic Characteristics of Patients with Breast Carcinoma in Nepal: A Single-Centre Cross Sectional Study".Acta Scientific Cancer Biology 9.4 (2025): 27-33.

Copyright

Copyright: © 2025 Adhikari Ganga D., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.