Muhamad Azamin Anuar*, Nur Farah Izzati Misaridin and Muhammad Shafiq Safwan Md Latip

Department of Pediatric, Sultan Ahmad Shah Medical Centre, International Islamic University Malaysia, Kuantan, Pahang, Malaysia

*Corresponding Author: Muhamad Azamin Anuar, Department of Pediatric, Sultan Ahmad Shah Medical Centre, International Islamic University Malaysia, Kuantan, Pahang, Malaysia.

Received: August 17, 2022; Published: September 05, 2022

Abstract

Bruising in the form of ecchymosis and purpura in a healthy child, should be taken into serious consideration when it occurs spontaneously with no logical explanation. Baseline blood investigations including blood film are mandatory to rule out malignancy. Thrombocytopenia is very common in pediatric population however platelet dysfunction is a challenging diagnosis that require extensive laboratory investigations. Acquired platelet dysfunction with eosinophilia is a syndrome that requires more awareness among pediatricians especially in Southeast Asia region to avoid parental anxiety. We report a three years old boy with a long history of spontaneous bruising that was eventually treated with anti-helminthic agent. The patient was seen by many clinicians over a period of time but unable to justify parental expectation and relieve their anxiety.

Keywords: Acquired Platelet Dysfunction with Eosinophilia; Ecchymosis; Bruises; Parental Anxiety; Parasites Infestation; Non-accidental Injury

References

1. Vora A and Makris M. “Personal practice: An approach to investigation of easy bruising”. Archives of Disease in Childhood 6 (2001): 488-491.
2. Mitrakul C. “Transient, spontaneous bruising with long bleeding time and normal platelet count”. American Journal of Clinical Pathology 1 (1975): 81-86.
3. Suvatte V., et al. “Acquired platelet dysfunction with eosinophilia: study of platelet function in 62 cases”. The Southeast Asian Journal of Tropical Medicine and Public Health3 (1979): 358-367.
4. Lee ACW. “Unusual hematologic disease affecting Caucasian children traveling to Southeast Asia: acquired platelet dysfunction with eosinophilia”. Hematology Reports1 (2012): e5.
5. Chotsampancharoen T., et al. “Clinical Course and Outcome of Childhood Acquired Platelet Dysfunction with Eosinophilia”. Acta Haematologica1 (2018): 28-32.
6. Kueh YK., et al. “Transient non-thrombocytopenic purpura in hookworm infestation”. Scandinavian Journal of Haematology 30 (1983): 174-176.
7. Ruiz-Saez A., et al. Platelet dysfunction-eosinophilia syndrome in parasitized Venezuelan children”. American Journal of Tropical Medicine and Hygiene 73 (2005): 381-385.
8. Singh BMK., et al. “Acquired platelet dysfunction with eosinophilia: a report of 3 cases with review of literature”. International Journal of Health Sciences and Research 8 (2014): 297-303
9. Chai JY., et al. “Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update”. The Korean journal of Parasitology3 (2021): 189-225.

Citation

Citation: Muhamad Azamin Anuar., et al. “Parental Anxiety to Unexplained Bruising: A Case Report of Acquired Platelet Dysfunction with Eosinophilia". Acta Scientific Women's Health 4.10 (2022): 09-12.

Copyright

Copyright: © 2022 Muhamad Azamin Anuar., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.