Binamra Sigdel¹*, Chitrathara Keshav², Sanam Puzhakkal³, VP Gangadharan⁴, Suresh Kayastha¹, Remi Abdul Shukur¹, Anupana S¹ and Tony Augustine¹

¹Fellow, Department of Surgical and Gynecological Oncology, VPS Lakeshore Hospital, Kochi, Kerala, India
²Consultant, Department of Surgical and Gynecological Oncology, VPS Lakeshore Hospital, Kochi, Kerala, India
³Associate Consultant, Department of Surgical and Gynecological Oncology, VPS Lakeshore Hospital, Kochi, Kerala, India
⁴Consultant, Department of Medical Oncology, VPS Lakeshore Hospital, Kochi, Kerala, India

*Corresponding Author: Binamra Sigdel, Fellow, Department of Surgical and Gynecological Oncology, VPS Lakeshore Hospital, Kochi, Kerala, India.

Received: April 08, 2021; Published: May 15, 2021

Abstract

Objective: The objective of this study is to evaluate oncological and reproductive outcome of epithelial ovarian cancers and its clinicopathological patterns in patients less than 30 years of age.

Methods: This is a retrospective, single center study and all the patients diagnosed with EOCs from 2014 to 2019 AD who underwent either primary surgery or completion surgery in this center were included in the study. Thirty-six patients with EOCs were identified and their clinicopathological characteristics, overall survival, progression free survival and reproductive outcomes were determined. Mean was used to describe continuous variables whereas frequency and percentages were used to describe categorical variables.

Results: The number of Epithelial Ovarian Cancers in women less than 30 years was 36 (8.07%). The mean age of the patients was 24. The most common mode of presentation was abdominal pain in cases followed by abdominal distension. The most common tumor subtypes were mucinous carcinoma followed by eight cases each of borderline serous and serous carcinoma. Most of the patients presented in early stage of disease. Twenty-two patients (61.12%) underwent fertility sparing surgery. Five patients had recurrence and there was one mortality. The median follow up period was 44 (14 - 90) months. Progression free survival was 37.41 months and overall survival was 44 months. The overall survival rate was 94.45%.

Conclusion: EOCs are rare in young patient and diagnosed at early stage. They have excellent prognosis with fertility sparing surgery and adjuvant chemotherapy and successful pregnancy can be achieved in most of the cases.

Keywords: Age Less Than Thirty Years; Malignant Epithelial Ovarian Cancer; Reproductive Outcome; Survival Outcome; Recurrence

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Citation

Citation: Binamra Sigdel., et al. “Oncological and Reproductive Outcome in Epithelial Ovarian Cancer in Women Less than 30 Years of Age". Acta Scientific Women's Health 3.6 (2021): 69-74.

Copyright

Copyright: © 2021 Binamra Sigdel., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.