Abstract

Objective: To describe the epidemiological, clinical and histological characteristics of breast cancer in Brazzaville

Materials and Method: This was a retrospective study carried out in the Medical Oncology Department of the Brazzaville University Hospital between January 2013 and December 2017. All the patients followed for histological breast cancer were included. Confirmed and having benefited from immunohistochemistry for hormone receptor assay and HER 2 status.

Results: Eighty-five patients were collected. The average age of the patients was 47.4 years with extremes of 22 and 73 years. The average consultation time was 7.9 months. The main reason for consultation was the finding or persistence of a breast nodule. Nonspecific infiltrating carcinoma was the most common histological type, and one case of medullary carcinoma was found. The histopronotic grades SBR I, II and III were respectively in 15.3%, 52.9% and 30.6% of the cases. Tumors of luminal type A and triple negative were the most representative, respectively 42.4% and 38.8%; tumors over expressing HER 2 were found in 10.6% and luminal B in 8.2% of cases. The majority of patients were in stage III (57.6%), 23.5% in stage II and 10.6% in stage IV. The median survival of the patients was 17 months for stage II, 25 months for stage III and 14 months for stage IV. According to the molecular groups, the median survival was 10 months for HER 2 (+) phenotype, 18 months for luminal A and B phenotypes and 28 months for the negative triple phenotype.

Conclusion: In the republic of Congo and more precisely in Brazzaville, breast cancer management remains difficult due to the lack of effective technical facilities and medical treatments.

Keywords: Breast Cancer; Immunohistochemistry; Brazzaville

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Citation

Citation: Ndounga E., et al. “Characteristics of Breast Cancers in Brazzaville: About 85 Cases”. Acta Scientific Women's Health 2.3 (2020): 11-17.

Copyright

Copyright: © 2020 Ndounga E., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.