Multiple Myeloma Presenting as Bilateral Foot Drop: A Diagnostic Dilemma
Ajay Kothari, Jenil Patel*, Pramod Bhilare and Parag Sancheti
Department of Spine Surgery, Sancheti Institute of Orthopaedics and Rehabilitation,
India
*Corresponding Author: Jenil Patel, Department of Spine Surgery, Sancheti
Institute of Orthopaedics and Rehabilitation, India.
Received:
September 14, 2023; Published: October 22, 2023
Abstract
Peripheral neuropathy is one of the commonest presentations seen in the spinal cord or vertebral column disorder. Injury to the
spinal cord, degenerative pathologies, osteomyelitis, malignancies, genetic disorders, viral infections, and vitamin deficiencies can
cause peripheral neuropathy secondary to spinal cord and vertebral column involvement.
Keywords: Multiple Myeloma; Bilateral Foot Drop; Diagnostic
References
- Chaudhry HM, Mauermann ML, Rajkumar SV. Monoclonal gammopathy–associated peripheral neuropathy: diagnosis and management. InMayo Clinic Proceedings 2017 May 1 (Vol. 92, No. 5, pp. 838-850). Elsevier.
- Plasmati R, Pastorelli F, Cavo M, Petracci E, Zamagni E, Tosi P, Cangini D, Tacchetti P, Salvi F, Bartolomei I, Michelucci R, Tassinari CA (2007) Neuropathy in multiple myeloma treated with thalidomide: a prospective study. Neurology 69:573–581
- Leone C, Federico V, La Cesa S, Russo E, Di Stefano G, Finsinger P, Labriola R, Cruccu G, Petrucci MT, Truini A (2016) An observational study assessing peripheral neuropathy related to multiple myeloma. Neurol Sci 37:1141–1143. https:// doi. org/10. 1007/ s10072- 016- 2542-9
- Walsh JC. The neuropathy of multiple myeloma: an electrophysiological and histiological study. Arch Neurol 1971; 25:404–414.
- 5) Dispenzieri A, Kyle RA (2005) Neurological aspects of multiple myeloma and related disorders. Best Pract Res Clin Haematol 18:673–688.
- Man HV, Dung PC. A Case of Multiple Myeloma in a 17-Year-Old Girl Treated with Autologous Hematopoietic Stem Cell Transplantation (ASCT). Am J Case Rep. 2019 Nov 5;20:1623-1629. doi: 10.12659/AJCR.917670. PMID: 31685790; PMCID: PMC6858627.
- Schembri EL, Mifsud S, Gauci J, Mizzi A, Fsadni P. An unusual presentation of multiple myeloma. BMJ Case Rep. 2018 Nov 28;11(1):e226412. doi: 10.1136/bcr-2018-226412. PMID: 30567104; PMCID: PMC6301485.
- Kumar SK, Mikhael JR, Buadi FK, et al. Management of newly diagnosed symptomatic multiple myeloma: updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus guidelines. Mayo Clin Proc. 2009;84:1095-1110.
- Molloy, C.B., Peck, R.A., Bonny, S.J. et al.An unusual presentation of multiple myeloma: a case report. J Med Case Reports 1, 84 (2007). https://doi.org/10.1186/1752-1947-1-84
- Kelley M A, Mestre A, Ayau M F, et al. (September 25, 2022) A Case Report of Non-secretory Multiple Myeloma. Cureus 14(9): e29571. doi:10.7759/cureus.29571
Citation
Copyright