B P S Tyagi¹ and Harsh Tyagi^2*

¹Professor, HOD, Department of ENT, Harsh ENT Hospital, Ghaziabad, India
²Consultant Dermatologist, Ambraja Skin Clinic, Ghaziabad, India

*Corresponding Author: Harsh Tyagi, Consultant Dermatologist, Ambraja Skin Clinic, Ghaziabad, India.

Received: April 24, 2026; Published: June 18, 2026

Background: Autologous plasma-derived biofillers are increasingly being explored as economical, biocompatible, and minimally invasive alternatives for soft-tissue augmentation. Their use has been described in facial rejuvenation and atrophic acne scars; however, their application in correction of secondary nasal contour deformities has been rarely reported.

Case Presentation: We report the case of a 20-year-old male with a postoperative contour deformity of the nose following surgery for juvenile angiofibroma performed 10 years earlier. The patient presented with a stable dorsal depression involving the middle third of the nose, resulting in aesthetic dissatisfaction.

Method: After detailed counselling and informed consent, autologous biofiller was prepared from the patient’s venous blood using plasma separation followed by thermal processing to obtain a gel-like filler material. The prepared biofiller was injected carefully into the deep plane over the depressed mid-nasal dorsum using a low-pressure, small-aliquot technique with strict attention to vascular safety.

Result: Immediate post-procedure assessment showed satisfactory correction of the dorsal depression with restoration of a smoother nasal contour. No immediate adverse effects such as blanching, severe pain, skin discoloration, or vascular compromise were observed. The patient remained satisfied on follow-up, with maintained cosmetic improvement.

Conclusion: This case highlights the potential utility of autologous biofiller as a simple, cost-effective, and minimally invasive option for correction of selected postoperative nasal contour deformities. Given the autologous nature, affordability, and prior dermatologic use of biofillers, they may represent a useful alternative in carefully selected patients; however, larger studies are needed to clarify durability, standardize preparation, and better define their role in nasal augmentation.

Keywords: Autologous Biofiller; Durability; Plasma Gel

References

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Citation

Citation: B P S Tyagi and Harsh Tyagi. “Use of Autologous Biofiller for Non-Surgical Nasal Augmentation: A Case Report". Acta Scientific Otolaryngology 8.5 (2026): 06-10.

Copyright

Copyright: © 2026 B P S Tyagi and Harsh Tyagi. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.