Acta Scientific Neurology (ISSN: 2582-1121)

Research Article Volume 5 Issue 5

Electroencephalography Aspects of Generalized Tonic-Clonic Seizures

Lemahafaka Jemissair Glorien1*, Rasaholiarison Nomena Finiavana2, Rajaonarison Lala Andriamasinavalona3 Amadou Gallo Diop1, Tehindrazanarivelo Alain Djacoba4

1Neurophysiology Unit, Teaching Hospital Fann Dakar
2Neurology Unit, Teaching Hospital Tambohobe, Fianarantsoa
3Neurology Unit, Teaching Hospital Place Kabary Antsiranana
4Neurology Unit, Teaching Hospital Joseph Raseta Befelatanana, Antananarivo

*Corresponding Author: Lemahafaka Jemissair Glorien, Neurophysiology Unit, Teaching Hospital Fann Dakar.

Received: March 04, 2022; Published: April 22, 2022



Introduction: Epilepsy is one of the most common serious chronic neurological diseases, affecting people of all ages worldwide. It is present in several clinical forms, of which the EEG constitutes a preferred examination for diagnosing this disease. This paper focuses on studying the results of the EEG requested for epilepsy and/or generalized tonic-clonic seizure in order to establish the electro-clinical correlation.

Materials and Methods: This is a retrospective and descriptive study that took place over a period of one year from July 2018 to June 2019 at the neurology department, CHU Fann Dakar.

Results: Out of 3960 patients seen during the study period, 295 patients were retained after inclusion and exclusion criteria. The average age was 10.32 years. The male predominance is noted in our study population with a sex ratio of 1.78. In 44.74% of cases, our patients lived in urban areas. Among our patients, 15.25% of the patients presented EEG signs in favor of generalized tonic-clonic seizures on the waking EEG and 38.98% on the sleep EEG.

Conclusion: The request for the EEG requires a rigorous clinical description and must be performed as early as possible to improve sensitivity. In the case of epilepsy or generalized tonic-clonic seizure, the clinical and electrical correlation was around 15 to 39% in the interictal EEG examinations in 48 hours after the last seizure. Some patients may have a normal EEG, which does not rule out the diagnosis of epilepsy and/or generalized tonic-clonic seizures, hence the importance of good clinical analysis in epilepsy.

Keywords: Tonic-Clonic Seizure; Epilepsy; EEG



  1. Christine T and Azulay JP. “Adult epilepsy; the neurology intern's book”. Lavoisier (2012): 307-331.
  2. Sadr SS., et al. “Descriptive epidemiology: prevalence, incidence, sociodemographic factors, socioeconomic domains, and quality of life of epilepsy: an update and systematic review”. Archives of Medical Science 4 (2018): 717-724.
  3. Bourrous M., et al. “Characteristics of children with epilepsy followed at the University Hospital of Marrakech”. Revue neurologique 166 (2010): 921-926.
  4. Taussig D and Biraben A. “Indications of the electroencephalogram”. EMC (Elsevier Masson SAS, Paris), Treatise on Medicine Akos (2011): 5-0841.
  5. Gursahani R and Gupta N. “The adolescent or adult with generalized tonic- clonic seizures”. Annals of Indian Academy of Neurology 2 (2012): 81-88.
  6. Celestin KM. “Epilepsies and acute epileptic seizures in children in sub-Saharan Africa: challenges and hopes”. Pan African Medical Journal 23 (2016):
  7. Prevett M. “Epilepsy in sub-Saharan African”. Practice Neurology1 (2013): 14-20.
  8. Kenneth Ayuurebobi Ae-Ngibise., et al. “Prevalence and risk factors for Active Convulsive Epilepsy in Kintampo, Ghana”. Pan African Medical Journal29 (2015): 1-9.
  9. Ba-Diop A., et al. “Epidemiology, causes, and treatment of epilepsy in sub-Saharan Africa”. Lancet Neurology10 (2014): 1029-1044.
  10. Beghi E. “The Epidemiology of Epilepsy”. Neuroepidemiology 54 (2020): 185-191.
  11. Symon M Kariuki., et al. “Acute seizures attributable to falciparum malaria in an endemic area on the Kenyan coast”. Brain5 (2011): 1519-1528.
  12. WHO, Global Burden of Epilepsy and the Need for Coordinated Action at Country Level to Influence its Health and Social Consequences and Raise Public Awareness, Sixty-eighth World Health Assembly (2011)?
  13. Zheng G., et al. “An epidemiological survey of epilepsy in tropical rural areas of China”. Epilepsia Open2 (2021): 323-330.
  14. Jaya Shankar Kaushik and Rajni Farmania. “Electroencephalography in Pediatric Epilepsy Indian”. Pediatrics 55 (2018): 893-901.
  15. Philippe Gelisse., et al. “Atlas of electroencephalography. Neurology and critical care - Volume 3. Paris: John Libbey Eurotext (2019).
  16. Mahmoud Al-Kadi., et al. “Evolution of Electroencephalogram Signal Analysis Techniques During Anesthesia”. Sensors (Basel) 5 (2013): 6605-6635.
  17. Nguefack S., et al. “Clinical, etiological and therapeutic aspects of febrile seizures: about 325 cases in Yaoundé”. Archives of Pediatrics 17 (2010): 480-485.
  18. Milh M. “First non-febrile epileptic seizure in children: definition, classification, place of additional examinations and management”. Emergencies 12 (2012): 1-9.


Citation: Lemahafaka Jemissair Glorien., et al. “Electroencephalography Aspects of Generalized Tonic-Clonic Seizures". Acta Scientific Neurology 5.5 (2022): 26-29.


Acceptance rate33%
Acceptance to publication20-30 days

Indexed In

News and Events

  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is June 25, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US