Ashwin Patel*, Hardik Patel and Lalit Patel

Department of Bioscience, Aajivi Pvt Ltd, Petlad, Anand, Gujarat, 388150, India

*Corresponding Author: Ashwin Patel, Department of Bioscience, Aajivi Pvt Ltd, Petlad, Anand, Gujarat, 388150, India.

Received: October 06, 2026; Published: November 02, 2026

Abstract

Objective: A high protein weight loss diet program (HP) vs a high carbohydrate weight loss diet (HC) program were used to treat obese subjects with newly diagnosed Type 2 Diabetes (T2DM) to determine the effects on remission of T2DM, cardiovascular risk factors (CVRs), incretins (GLP-1, GIP), inflammation (IC), metabolic parameters, and muscle and fat body mass.
Research Design and Methods: Twenty-four obese women and men newly diagnosed with T2DM on no medications treatments were recruited and randomized to either a high protein-low carbohydrate (HP) (12 subjects) or a high carbohydrate-low protein (HC) (12 subjects) weight loss programs for 6 months in this randomized controlled clinical trial. Subjects were provided all foods for 6 months with daily meal menus which were dispensed weekly along with weight determinations. At baseline Oral Glucose Tolerance Test (OGTT) and Meal Tolerance Test (MTT) and DXA were done with determinations of glucose, insulin, inflammatory markers (IC), CVRs, incretin (GLP-1, GIP), and repeated after 6 months on the subjects on the respective diets.
Results: After 6 months on the HP diet program100% of the subjects had remission of their T2DM to Normal Glucose Tolerance (NGT), whereas only 8% of subjects on the HC diet had remission of T2DM, although both subject groups had similar significant weight losses. Insulin sensitivity, Cardiovascular risk factors, inflammatory cytokines and incretins (GLP-1, GIP) all exhibited significant improvements along with increased per cent muscle body mass with the HP compared to the HC diet group which lost muscle mass at 6 months.
Conclusion: Subjects on the HP weight loss diet program achieved 100% remission of T2DM to NGT at 6 months along with significant improvements in cardiovascular risk factors, incretins, inflammation, metabolic parameters, and muscle retention compared to the HC weight loss diet program. These improvements with the HP weight loss diet were achieved using foods available at local grocery stores at a cost of only $15 per day.

Keywords: Insulin Sensitivity; High Protein Weight Loss Diet; Exercise; Cardiovascular Risk Markers; Incretins; Inflammatory Markers

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Citation

Citation: Ashwin Patel., et al. “Effect of Aajivi PRO MYCO Formulated Using SEU Technology on Growth, Tuber Yield, and Nutrient Uptake in Potato (Solanum tuberosum L.)". Acta Scientific Microbiology 9.11 (2026): 23-31.

Copyright

Copyright: © 2026 Ashwin Patel., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.