Robert M Beatty*, Shelley Smith Beatty and Beatty LLC

3800 West 57th Terrace, Fairway, KS 66205, USA

*Corresponding Author: Robert M Beatty, 3800 West 57th Terrace, Fairway, KS 66205, USA

Received: September 24, 2026; Published: October 12, 2026

Abstract

A theory of the mechanism of long COVID-19 is presented. Even though long COVID-19 can present a variety of symptoms, a universal mechanism is involved in each case and is discussed in this paper. Also presented is the role of acyclovir and how it can alleviate the diverse symptoms of long COVID-19. Although long COVID-19 is multifaceted, meaning it affects many organ systems, the mechanism is universal based upon the immune response seen in wound healing.

Keywords: COVID-19; Long COVID-19; Immune Response; Fabrin Net; Foreign Body; Acyclovir

References

1. Davis HE., et al. “Long COVID: major findings, mechanisms and recommendations”. Nature Reviews Microbiology3 (2023): 133-146.
2. Almadani YH., et al. “Wound Healing: A Comprehensive Review”. Seminars in Plastic Surgery3 (2021): 141-144.
3. Alizon S and Sofonea MT. “SARS-CoV-2 virulence evolution: Avirulence theory, immunity and trade-offs”. Journal of Evolutionary Biology 12 (2021): 1867-1877.
4. Sinno H and Prakash S. “Complements and the wound healing cascade: an updated review”. Plastic Surgery International 2013 (2013): 146764.
5. Ryu JK., et al. “Fibrin drives thromboinflammation and neuropathology in COVID-19”. Nature 633 (2024): 905-913.
6. Beatty RM. “Long COVID-19 Symptoms Remedied by Anti-Viral Treatment in Neurosurgical Patients”. American Journal of Infectious Diseases3 (2023): 39-44.

Citation

Citation: Robert M Beatty., et al. “The Pathophysiology of Long COVID-19 Illness and Acyclovir". Acta Scientific Microbiology 9.11 (2026): 04-07.

Copyright

Copyright: © 2026 Robert M Beatty., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.